PSS15 – Economic Evaluation for The Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) From The NHS Perspective: A Spending Predictor Model for Italy, Romania and Spain

Objectives Dalbavancin is a new innovative long-acting antimicrobial treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) that allows clinicians to endorse an early discharge (ED) approach. Aim of this study was to develop a spending predictor model for evaluating the direct costs associated with the management of ABSSSI from a National Payer perspective…

Impacto del dolor crónico discapacitante: resultados de un estudio poblacional transversal con entrevista cara a cara

Objetivo Conocer el impacto del dolor crónico discapacitante (DCD) en la calidad de vida, el trabajo, el consumo de medicamentos y la utilización de servicios sanitarios. Diseño Estudio poblacional transversal con entrevista cara a cara y diseño muestral complejo. Emplazamiento Encuesta Andaluza de Salud (edición 2011). Participantes Un total de 6.507 personas ≥ 16 años (p = q = 0,5; nivel…

Priorities for health economic methodological research: results of an expert consultation

Background: The importance of economic evaluation in decision making is growing with increasing budgetary pressures on health systems. Diverse economic evidence is available for a range of interventions across national contexts within Europe, but little attention has been given to identifying evidence gaps that, if filled, could contribute to more efficient allocation of resources. One…

Humanizar la sanidad para mejorar la calidad de sus servicios

La palabra «humanizar» es un término moderno que ha sustituido al viejo vocablo «humanar» cuyo significado según el diccionario de María Moliner es hacer una cosa más humana, menos cruel, menos dura para los hombres. Su raíz se encuentra en el término «humanidad» definible según el diccionario de la Real Academia Española como sensibilidad, compasión,…

Expression of placental regulatory genes is associated with fetal growth

The placenta is the principal organ regulating respiratory, nutritional, endocrine and metabolic functions on behalf of the developing fetus. Changes in gene expression patterns of placenta-specific genes may influence fetal growth. We profiled the expression of 17 genes related to placenta functioning in term placentas (n=677) to identify genes differentially expressed across birth weight categories…

Socio-demographic, lifestyle, and dietary determinants of essential and possibly-essential trace element levels in adipose tissue from an adult cohort

There is increasing evidence linking levels of trace elements (TEs) in adipose tissue with certain chronic conditions (e.g., diabetes or obesity). The objectives of this study were to assess concentrations of a selection of nine essential and possibly-essential TEs in adipose tissue samples from an adult cohort and to explore their socio-demographic, dietary, and lifestyle…

Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort

Background: There is convincing evidence that high physical activity lowers the risk of colon cancer; however, the underlying biological mechanisms remain largely unknown. We aimed to determine the extent to which body fatness and biomarkers of various biologically plausible pathways account for the association between physical activity and colon cancer.Methods: We conducted a nested case-control…