Identificación de indicadores de buenas prácticas en gestión clínica y sanitaria

Objetivo Identificar buenas prácticas para desarrollar e implementar indicadores de resultados en salud para la gestión clínica y sanitaria. Metodología Revisión exploratoria de la literatura (scoping review), con las fases: 1) búsqueda e identificación de bibliografía; 2) selección de documentos relevantes. Se incluyeron estudios que discutían buenas prácticas para la utilización de indicadores en salud…

Tumor-associated auto-antibodies as early detection markers for ovarian cancer? A prospective evaluation

Immuno-proteomic screening has identified several tumor-associated auto-antibodies (AAb) that may have diagnostic capacity for invasive epithelial ovarian cancer, with AAbs to P53 proteins and cancer-testis antigens (CTAGs) as prominent examples. However, the early detection potential of these AAbs has been insufficiently explored in prospective studies. We performed ELISA measurements of AAbs to CTAG1A, CTAG2, P53,…

Trends in incidence of thick, thin and in situ melanoma in Europe

Background We analysed trends in incidence for in situ and invasive melanoma in some European countries during the period 1995–2012, stratifying for lesion thickness. Material and methods Individual anonymised data from population-based European cancer registries (CRs) were collected and combined in a common database, including information on age, sex, year of diagnosis, histological type, tumour…

Analysis of changes in trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs

Background To analyse trends in the rates of consumption of benzodiazepine (BZD) anxiolytics, BZD hypnotics and non-BZD hypnotics and the association with contextual factors. Methods Descriptive time series study. Units of analysis were monthly dose per inhabitant per day (DID) and dose per medical card per day(DCD) of benzodiazepine(BZD anxiolytics(BZD-A), BZD hypnotics(BZD-H) and non-BZD hypnotics(Non-BZD-H)…