Demographic, lifestyle, and other factors in relation to antimüllerian hormone levels in mostly late premenopausal women

Objective To identify reproductive, lifestyle, hormonal, and other correlates of circulating antimüllerian hormone (AMH) concentrations in mostly late premenopausal women. Design Cross-sectional study. Setting Not applicable. Patient(s) A total of 671 premenopausal women not known to have cancer. Intervention(s) None. Main Outcome Measure(s) Concentrations of AMH were measured in a single laboratory using the picoAMH…

Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohort

Background Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening. Methods We evaluated cross-sectional relationships between lifestyle and reproductive factors and these markers among controls (n = 1910) from a nested case-control study in the European Prospective Investigation into Cancer and Nutrition (EPIC). Improvements in discrimination of…

Valoración de aspectos éticos y metodológicos en un estudio cualitativo con personas usuarias de Oncología Pediátrica

Fundamentos: En el marco de una investigación cualitativa con personas usuarias de Oncología Pediátrica y sus acompañantes, se diseñó y aplicó un instrumento de autoevaluación sobre aspectos éticos y metodológicos del estudio. Métodos: Investigación cualitativa con personas usuarias de Oncología Pediátrica y sus acompañantes, en cuatro Hospitales del Sistema Sanitario Público de Andalucía. Elaboración y…

Socio-economic factors linked with mental health during the recession: a multilevel analysis

Background Periods of financial crisis are associated with higher psychological stress among the population and greater use of mental health services. The objective is to analyse contextual factors associated with mental health among the Spanish population during the recession. Methodology Cross-sectional, descriptive study of two periods: before the recession (2006) and after therecession (2011-2012). The…

The association between adult attained height and sitting height with mortality in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly associated with insulin resistance;…

Editorial Repensar la Carta de Ottawa 30 años después

A 30 años de la Carta de Ottawa1 para la promoción de la salud, aprobada en noviembre de 1986, es válido preguntarse cómo ha logrado influenciar las políticas de salud pública o específicamente, como señala la Carta, «avanzar hacia una nueva salud pública»2. Cada efeméride de la Carta de Ottawa se escriben editoriales o suplementos…

Coffee, tea and melanoma risk: findings from the European Prospective Investigation into Cancer and Nutrition

n vitro and animal studies suggest that bioactive constituents of coffee and tea may have anticarcinogenic effects against cutaneous melanoma; however, epidemiological evidence is limited to date. We examined the relationships between coffee (total, caffeinated or decaffeinated) and tea consumption and risk of melanoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC…