Incidence and survival time trends for Spanish children and adolescents with leukaemia from 1983 to 2007

Objective We have analysed incidence and survival trends of children and adolescents with leukaemia registered in Spanish population-based cancer registries during the period 1983–2007. Methods Childhood and adolescent leukaemia cases were drawn from the 11 Spanish population-based cancer registries. For survival, registries with data for the period 1991–2005 and follow-up until 31-12-2010 were included. Overall…

Prevalencia de la violencia de parejas en España: estudio transversal a través de cuestionario en la atención primaria

Objetivos 1) Analizar la prevalencia de Violencia de Pareja por tipos. 2) Examinar la relación entre las características sociodemográficas y la Violencia de Pareja. Diseño Estudio transversal a través de cuestionario autoadministrado. Emplazamiento Centros de Atención Primaria en España. Participantes 10.322 mujeres (de 18 a 70 años) asistentes a Centros de Atención Primaria. Mediciones principales…

Prediagnostic selenium status and hepatobiliary cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort

Background: Selenium status is suboptimal in many Europeans and may be a risk factor for the development of various cancers, including those of the liver and biliary tract. Objective: We wished to examine whether selenium status in advance of cancer onset is associated with hepatobiliary cancers in the EPIC (European Prospective Investigation into Cancer and…

Comparison of abdominal adiposity and overall obesity in relation to risk of small intestinal cancer in a European Prospective Cohort

The etiology of small intestinal cancer (SIC) is largely unknown, and there are very few epidemiological studies published to date. No studies have investigated abdominal adiposity in relation to SIC. Methods We investigated overall obesity and abdominal adiposity in relation to SIC in the European Prospective Investigation into Cancer and Nutrition (EPIC), a large prospective…

Adoption of trastuzumab for breast cancer in four emerging countries in the use of health technology assessment: a case study

Aim: To describe processes for the adoption of trastuzumab in four countries in the use of health technology assessment (HTA): Poland, Albania, Brazil and Colombia. Materials & methods: Mixed methods were used for collection and triangulation of data. Data were examined following a conceptual framework connecting HTA process steps and key principles. Results: Trastuzumab was…

Adoption of trastuzumab for breast cancer in four emerging countries in the use of health technology assessment: a case study

Regulatory authorities have indicated that new drugs to treat type 2 diabetes (T2D) should not be associated with an unacceptable increase in cardiovascular risk. Human genetics may be able to guide development of antidiabetic therapies by predicting cardiovascular and other health endpoints. We therefore investigated the association of variants in six genes that encode drug…