Social support buffers the negative effects of stress in cardiac patients: a cross-sectional study with acute coronary syndrome patients

Cardiac patients who have social support generally have better prognosis than patients who lack social support. Several theoretical mechanisms have been proposed to explain this protective effect, including the capacity of social support to buffer the negative effects of stress. We tested this buffering effect in a study of patients hospitalized for acute coronary syndrome…

Interaction between MTHFR 677C>T, PON1 192Q>R and PON1 55L>M polymorphisms and its effect on non-recurrent spontaneous abortion in Mexican women

MTHFR is a key enzyme in folate metabolism. Some genetic polymorphisms code for a less efficient enzyme, increasing serum concentrations of homocysteine. This has been associated with inadequate feto-maternal circulation and increased risk of spontaneous abortion. Paroxonase 1 (PON1) is a multifunctional enzyme that can detoxify homocysteine through its homocysteine thiolactonase activity. We evaluate the…

Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Purpose Coffee and tea constituents have shown several anti-carcinogenic activities in cellular and animal studies, including against thyroid cancer (TC). However, epidemiological evidence is still limited and inconsistent. Therefore, we aimed to investigate this association in a large prospective study. Methods The study was conducted in the EPIC (European Prospective Investigation into Cancer and Nutrition)…

Risk prediction for estrogen receptor-specific breast cancers in two large prospective cohorts

Background Few published breast cancer (BC) risk prediction models consider the heterogeneity of predictor variables between estrogen-receptor positive (ER+) and negative (ER-) tumors. Using data from two large cohorts, we examined whether modeling this heterogeneity could improve prediction. Methods We built two models, for ER+ (ModelER+) and ER- tumors (ModelER-), respectively, in 281,330 women (51%…

Heroína, pero no Superwoman. Evaluación de una formación entre iguales para mujeres con cáncer de mama

Objetivo Evaluar una actividad formativa entre iguales para pacientes con cáncer de mama desde la perspectiva de género; conocer los resultados y profundizar en las experiencias de pacientes y profesionales sanitarios participantes. Método: Diseño multicéntrico mixto (Andalucía, 2017) con un cuestionario de evaluación pretest/postest con 102 pacientes formadas, midiendo hábitos de vida, limitaciones, uso y…

How are risk ratios reported in orthopaedic surgery journals? A descriptive study of formats used to report absolute risks

Purpose The numerical format in which risks are communicated can affect risk comprehension and perceptions of medical professionals. We investigated what numerical formats are used to report absolute risks in empirical articles, estimated the frequency of biasing formats and rated the quality of figures used to display the risks. Design Descriptive study of reporting practices.…

Desarrollo de un mapa de riesgos para la tomografía por emisión de positrones

La seguridad del paciente es un componente esencial de la calidad asistencial, especialmente cuando la complejidad de la asistencia ha alcanzado niveles extremos. En la actualidad, conseguir esta seguridad se considera una estrategia básica del sistema nacional de salud. Los servicios de Medicina Nuclear muestran unas particularidades que los hacen especiales en materia de seguridad…

Derechos de las personas trans e intersex: revisión del marco legislativo en el contexto español desde una perspectiva de despatologización y derechos humanos

El objetivo de este trabajo es revisar los derechos de las personas trans e intersex en la legislación actualmente vigente en el contexto español, tomando como referencia las recomendaciones establecidas por organismos internacionales y regionales de derechos humanos y las demandas expresadas por el activismo internacional por la despatologización trans y el movimiento intersex internacional.…