Interaction between MTHFR 677C>T, PON1 192Q>R and PON1 55L>M polymorphisms and its effect on non-recurrent spontaneous abortion in Mexican women

MTHFR is a key enzyme in folate metabolism. Some genetic polymorphisms code for a less efficient enzyme, increasing serum concentrations of homocysteine. This has been associated with inadequate feto-maternal circulation and increased risk of spontaneous abortion. Paroxonase 1 (PON1) is a multifunctional enzyme that can detoxify homocysteine through its homocysteine thiolactonase activity. We evaluate the…

Interaction Between GAD65 Antibodies and Dietary Fish Intake or Plasma Phospholipid n-3 Polyunsaturated Fatty Acids on Incident Adult-Onset Diabetes: The EPIC-InterAct Study

OBJECTIVE Islet autoimmunity is associated with diabetes incidence. We investigated whether there was an interaction between dietary fish intake or plasma phospholipid n-3 polyunsaturated fatty acid (PUFA) concentration with the 65-kDa isoform of GAD (GAD65) antibody positivity on the risk of developing adult-onset diabetes. RESEARCH DESIGN AND METHODS We used prospective data on 11,247 incident…

Intensive alcohol consumption by adolescents in Southern Spain: The importance of friendship

Background There has been an increase in intensive alcohol drinking by Spanish adolescents since the 1990s, especially among the females, but there has been limited exploration of this phenomenon. The objective of this study was to analyse the discourses of Spanish adolescents on their drinking behaviour at contextual, relational, and personal levels. Methods A qualitative…

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

Insulin resistance is a key mediator of obesity-related cardiometabolic disease, yet the mechanisms underlying this link remain obscure. Using an integrative genomic approach, we identify 53 genomic regions associated with insulin resistance phenotypes (higher fasting insulin levels adjusted for BMI, lower HDL cholesterol levels and higher triglyceride levels) and provide evidence that their link with…

Intake of Individual Fatty Acids and Risk of Prostate Cancer in the European Prospective Investigation into Cancer and Nutrition

The associations of individual dietary fatty acids with prostate cancer risk have not been examined comprehensively. We examined the prospective association of individual dietary fatty acids with prostate cancer risk overall, by tumor subtypes, and prostate cancer death. 142,239 men from the European Prospective Investigation into Cancer and Nutrition who were free from cancer at…

Informe I Jornada sobre avances en cáncer de pulmón EASP

El 11 de mayo de 2017 se celebró en Granada, en la sede de la Escuela Andaluza de Salud Pública (EASP), la Primera Jornada sobre avances en cáncer de pulmón, dirigida a profesionales de Neumología, Cirugía Torácica, Anatomía Patológica, Oncología, Genética, Radiología, Farmacia Hospitalaria, Atención Primaria, etc., además de profesionales y gestores directivos de Andalucía.…

Informe de Salud y Género 2022

DESCARGA INFORME PDFPÁGINA WEB Propuesta de citación de la publicación: López Rodríguez Rosa Mª, Soriano Villarroel Isabel, Coord. Informe Salud y Género 2022: aproximación multidisciplinar a la pandemia por COVID-19. Madrid: Ministerio de Sanidad; 2022 Dirección General de Salud Pública: Pilar Aparicio Azcárraga. Directora General Coordinación del Informe: Rosa Mª López Rodríguez. Directora de Programas…

Influencia del código postal en las hospitalizaciones pediátricas en Sevilla

Introducción El lugar de vivienda es un indicador del nivel socioeconómico que influye en la morbimortalidad y utilización de recursos sanitarios. Los objetivos de este estudio fueron analizar este efecto en las hospitalizaciones pediátricas y describir las tasas de hospitalización de los diagnósticos principales más frecuentes en la ciudad de Sevilla. Material y métodos Estudio…

Influencia de la temperatura ambiental y contaminación en la transmisión del SARS-COV-2

La transmisión del SARS-CoV-2 es un problema de Salud Pública de máxima importancia que está influido por diversos factores. Recientemente se ha planteado la hipótesis de que esta transmisión puede reducirse durante el verano debido a la temperatura cálida. Por otro lado, se está estudiando la posible relación entre el elevado número de contagios de…