Absolute Risk of Oropharyngeal Cancer After an HPV16-E6 Serology Test and Potential Implications for Screening: Results From the Human Papillomavirus Cancer Cohort Consortium

PURPOSE Seropositivity for the HPV16-E6 oncoprotein is a promising marker for early detection of oropharyngeal cancer (OPC), but the absolute risk of OPC after a positive or negative test is unknown. METHODS We constructed an OPC risk prediction model that integrates (1) relative odds of OPC for HPV16-E6 serostatus and cigarette smoking from the human…

Absolute Risk of Oropharyngeal Cancer After an HPV16-E6 Serology Test and Potential Implications for Screening: Results From the Human Papillomavirus Cancer Cohort Consortium

PURPOSE Seropositivity for the HPV16-E6 oncoprotein is a promising marker for early detection of oropharyngeal cancer (OPC), but the absolute risk of OPC after a positive or negative test is unknown. METHODS We constructed an OPC risk prediction model that integrates (1) relative odds of OPC for HPV16-E6 serostatus and cigarette smoking from the human…

Acabar con la pobreza

La reducción de la pobreza es una obligación para todos los gobiernos del planeta y un deber ético para la ciudadanía del mundo. La pobreza actual, que alcanza a la mitad de la población mundial degrada la condición humana. De los retos relacionados con la reducción de la pobreza y las estrategias más adecuadas para…

Acceptance or decline of requests to review manuscripts: A gender-based approach from a public health journal

Peer review in the scientific publication is widely used as a method to identify valuable knowledge. Editors have the task of selecting appropriate reviewers. We assessed the reasons given by potential reviewers for declining a request to review, and the factors associated with acceptance, taking into account the difference in the sex of the reviewer.…

Acción Comunitaria para ganar Salud

Guía Acción Comunitaria para ganar Salud…o cómo trabajar en común para mejorar las condiciones de vida Coordinación institucional: Ministerio de Sanidad. Dirección General de Salud Pública. Subdirección General de Promoción, Prevención y Calidad Coordinación técnica: Mariano Hernán García. Escuela Andaluza de Salud Pública Jara Cubillo Llanes. Ministerio de Sanidad ¿A quién se dirige esta guía?…

Acrylamide and glycidamide hemoglobin adduct levels and endometrial cancer risk: A nested case-control study in non-smoking postmenopausal women from the EPIC cohort

Acrylamide, classified in 1994 by IARC as ‘probably carcinogenic to humans’, was discovered in 2002 in some heat-treated, carbohydrate-rich foods. Four prospective studies have evaluated the association between dietary acrylamide intake and endometrial cancer (EC) risk with inconsistent results. The purpose of this nested case-control study, based on the European Prospective Investigation into Cancer and…

Activity and determinants of cholinesterases and paraoxonase-1 in blood of workers exposed to non-cholinesterase inhibiting pesticides

Pesticide exposure has been associated with different adverse health effects which may be modulated to some extent by paraoxonase-1 (PON1) activity and genetic polymorphisms. This study assessed seasonal variations in PON1 activity (using paraoxon –POase–, phenylacetate –AREase–, diazoxon –DZOase– and dihydrocoumarin –DHCase– as substrates), erythrocyte acetylcholinesterase (AChE) and plasma cholinesterase (using butyrylthiocholine –BuChE– and benzoylcholine…