Derechos de las personas trans e intersex: revisión del marco legislativo en el contexto español desde una perspectiva de despatologización y derechos humanos

El objetivo de este trabajo es revisar los derechos de las personas trans e intersex en la legislación actualmente vigente en el contexto español, tomando como referencia las recomendaciones establecidas por organismos internacionales y regionales de derechos humanos y las demandas expresadas por el activismo internacional por la despatologización trans y el movimiento intersex internacional.…

Deprivation gap in colorectal cancer survival attributable to stage at diagnosis: A population-based study in Spain

Objective Socioeconomic inequalities in colorectal cancer (CRC) survival are a major concern of the Spanish public health system. If these inequalities were mainly due to differences in stage at diagnosis, population-based screening programs might reduce them substantially. We aimed to determine to what extent adverse stage distribution contributed to survival inequalities in a Spanish region…

Depathologising gender diversity in childhood in the process of ICD revision and reform

From 2007 on, the World Health Organisation (WHO) has been revising its diagnostic manual, the International Statistical Classification of Diseases and Related Health Problems (ICD), with approval of ICD-11 due in 2018. The ICD revision has prompted debates on diagnostic classifications related to gender diversity and gender development processes, and specifically on the ‘Gender incongruence…

Demographic, lifestyle, and other factors in relation to antimüllerian hormone levels in mostly late premenopausal women

Objective To identify reproductive, lifestyle, hormonal, and other correlates of circulating antimüllerian hormone (AMH) concentrations in mostly late premenopausal women. Design Cross-sectional study. Setting Not applicable. Patient(s) A total of 671 premenopausal women not known to have cancer. Intervention(s) None. Main Outcome Measure(s) Concentrations of AMH were measured in a single laboratory using the picoAMH…

Democratising diagnoses? The role of the depathologisation perspective in constructing corporeal trans citizenship

In the scope of the current revision process of the diagnostic manuals Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Statistical Classification of Diseases and Other Health Problems (ICD), an international trans depathologisation movement has emerged that demands, among other claims, the removal of a diagnostic classification of gender transition processes as a…

DatAC: A visual analytics platform to explore climate and air quality indicators associated with the COVID-19 pandemic in Spain

The coronavirus disease 2019 (COVID-19) pandemic has caused an unprecedented global health crisis, with several countries imposing lockdowns to control the coronavirus spread. Important research efforts are focused on evaluating the association of environmental factors with the survival and spread of the virus and different works have been published, with contradictory results in some cases.…

Dairy Product Intake and Risk of Type 2 Diabetes in EPIC-InterAct: A Mendelian Randomization Study

OBJECTIVE To estimate the causal association between intake of dairy products and incident type 2 diabetes. RESEARCH DESIGN AND METHODS The analysis included 21,820 European individuals (9,686 diabetes cases) of the EPIC-InterAct case-cohort study. Participants were genotyped, and rs4988235 (LCT-12910C>T), a SNP for lactase persistence (LP) which enables digestion of dairy sugar, i.e., lactose, was…

cvauroc: Command to compute cross-validated area under the curve for ROC analysis after predictive modeling for binary outcomes

Receiver operating characteristic (ROC) analysis is used for comparing predictive models in both model selection and model evaluation. ROC analysis is often applied in clinical medicine and social science to assess the tradeoff between model sensitivity and specificity. After fitting a binary logistic or probit regression model with a set of independent variables, the predictive…