Approach to identifying research gaps on vector-borne and other infectious diseases of poverty in urban settings: scoping review protocol from the VERDAS consortium and reflections on the project’s implementation

Background This paper presents the overall approach undertaken by the “VEctor boRne DiseAses Scoping reviews” (VERDAS) consortium in response to a call issued by the Vectors, Environment and Society unit of the Special Programme for Research and Training in Tropical Diseases hosted by the World Health Organization. The aim of the project was to undertake…

Are costs derived from diagnosis-related groups suitable for use in economic evaluations? A comparison across nine European countries in the European Healthcare and Social Cost Database

Background Economic evaluation of health technologies requires healthcare resources, procedures and services to be valued at their opportunity cost. In practice, many economic evaluation studies use official databases of hospital Diagnosis-Related Groups (DRGs) as inputs where unit costs are required. This study describes the available data on costs of hospital DRG from official, publicly available…

Aromatic DNA adducts and breast cancer risk: a case-cohort study within the EPIC-Spain

Epidemiologic evidence linking environmental exposure to polycyclic aromatic hydrocarbons (PAH) with breast cancer is limited. Measurement of DNA adducts formed by aromatic compounds, including PAH, has been carried in breast tissue samples and white blood cells from women with breast cancer and different kinds of controls. However, these studies provide inconsistent results and bias cannot…

Arquitectura sanitaria en el Sistema Sanitario Público de Andalucía: Guía de diseño del Servicio de Urgencias de hospitales. Edición 2018

Título: Arquitectura sanitaria en el Sistema Sanitario Público de Andalucía: Guía de diseño del Servicio de Urgencias de Hospitales. Edición 2018 Autor: Servicio Andaluz de Salud y Escuela Andaluza de Salud Pública Resumen: La información que contiene esta Guía define una base común para proyectar el diseño arquitectónico del Servicio de Urgencias de los distintos hospitales del Sistema…

Arquitectura Sanitaria en el Sistema Sanitario Público de Andalucía. Guía de diseño de Radiodiagnóstico Hospitalario

Título: Arquitectura sanitaria en el Sistema Sanitario Público de Andalucía: Guía de diseño de radiodiagnóstico hospitalario. Edición 2016 Autor: Servicio Andaluz de Salud y Escuela Andaluza de Salud Pública Resumen: La información que contiene esta Guía define una base común para proyectar el diseño arquitectónico del Área de Radiodiagnóstico de los distintos hospitales del Sistema Sanitario Público de…

Asociación entre la caminabilidad del barrio de residencia y la mortalidad por distintas causas en Andalucía

Objetivo Describir la asociación entre la caminabilidad del barrio de residencia y la mortalidad. Método Estudio ecológico de áreas pequeñas. Se calcularon las razones de mortalidad estandarizadas (RME) y el Walk Score© en cada sección censal. Los valores se compararon con pruebas paramétricas y no paramétricas. Resultados En los hombres, las RME medias para enfermedades…

Assessing Potentially Inappropriate Prescribing in Community-Dwelling Older Patients Using the Updated Version of STOPP-START Criteria: A Comparison of Profiles and Prevalences with Respect to the Original Version

Emerging and changing evidence made it necessary to update STOPP-START criteria, and version 2 was published recently. In this study the objectives were to determine the prevalence of potentially inappropriate medication prescribing (PIM) in primary care using STOPP versions 1 (v1) and 2 (v2), as well as 2012 AGS Beers criteria, and analyze the factors…

Assessing Prevalence and Factors Related to Frailty in Community-Dwelling Older Adults: A Multinomial Logistic Analysis

Frailty is an age-related clinical condition that typically involves a deterioration in the physiological capacity of various organ systems and heightens the patient’s susceptibility to stressors. For this reason, one of the main research goals currently being addressed is that of characterising the impact of frailty in different settings. The main aim of this study…

Assessing the Consequences of External Reference Pricing for Global Access to Medicines and Innovation: Economic Analysis and Policy Implications

Background: External reference pricing (ERP) is used to set pharmaceutical prices to improve affordability, but its application may have negative consequences on patient access—thus, equity—across countries and on global innovation. With the United States contemplating ERP, negative effects could be magnified. Our aim: identify and quantify some major consequences of ERP. Research design, methods: Besides…

Assessing the value contribution of bimekizumab for the treatment of moderate-to-severe psoriasis using a multidisciplinary reflective multi-criteria decision analysis

Background Multi-criteria decision analysis (MCDA) was proposed to surmount arbitrary clinical decisions in the field of biological therapies for psoriatic patients. At the same time, MCDA may further highlight the potential of bimekizumab for the treatment of moderate-to-severe psoriasis, compared to placebo, adalimumab, ustekinumab, secukinumab, and even ixekizumab and risankizumab. Research design and methods The…