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Calibration and XGBoost reweighting to reduce coverage and non-response biases in overlapping panel surveys: application to the Healthcare and Social Survey

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background Surveys have been used worldwide to provide information on the COVID-19 pandemic impact so as to prepare and deliver an effective Public Health response. Overlapping panel surveys allow longitudinal estimates and more accurate cross-sectional estimates to be obtained thanks to the larger sample size. However, the problem of non-response is particularly aggravated in the…

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Circulating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women

Artículos Científicos, Cáncer, Investigación

Thyroid cancer (TC) is substantially more common in women than in men, pointing to a possible role of sex steroid hormones. We investigated the association between circulating sex steroid hormones, sex hormone binding globulin (SHBG) and the risk of differentiated TC in men and women within the European Prospective Investigation into Cancer and nutrition (EPIC)…

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Arquitectura Sanitaria en el Sistema Sanitario Público de Andalucía

Publicaciones EASP

ARQUITECTURA SANITARIA EN EL SISTEMA SANITARIO PÚBLICO DE ANDALUCÍA GUÍA DE DISEÑO DE CENTROS DE ATENCIÓN PRIMARIA Esta Guía de Diseño tiene por objeto aportar información a los equipos profesionales que intervienen el diseño arquitectónico o remodelación de los centros de atención primaria del SAS. Está dirigida tanto a profesionales técnicos del ámbito de la…

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Estudio sobre el mercado de medicamentos biosimilares en el Sistema Nacional de Salud en España

Medicamentos, Publicaciones EASP

Equipo del proyecto Coordinación Jaime Espín, PhD Profesor. Escuela Andaluza de Salud Pública Equipo técnico Leticia García Mochón, PhD Técnica de Proyectos. Escuela Andaluza de Salud Pública Zuzana Špacírová, PhD Técnica de Proyectos. Escuela Andaluza de Salud Pública Revisores Félix Lobo Aleu Profesor Emérito. Universidad Carlos III de Madrid Marta Trapero Bertran Profesora. Universidad de…

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Dietary intake of dicarbonyl compounds and changes in body weight over time in a large cohort of European adults

Artículos Científicos, Cáncer, Igualdad, Investigación

Dicarbonyl compounds are highly reactive precursors of Advanced Glycation End-products (AGEs), produced endogenously, present in certain foods, and formed during food processing. AGEs contribute to development of adverse metabolic outcomes but health effects of dietary dicarbonyls are largely unexplored. We investigated associations between three dietary dicarbonyl compounds, methylglyoxal (MGO), glyoxal (GO), and 3-deoxyglucosone (3-DG), and…

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Surgical Treatment in Post-Stroke Spastic Hands: A Systematic Review

Artículos Científicos

Background: For more than two decades, the surgical treatment of post-stroke spastic hands has been displaced by botulinum toxin therapy and is currently underutilized. Objectives: This article aimed to assess the potential of surgery for treating a post-stroke spastic upper extremity through a systematic review of the literature on surgical approaches that are adopted in…

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Association between pre-diagnostic circulating lipid metabolites and colorectal cancer risk: a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Altered lipid metabolism is a hallmark of cancer development. However, the role of specific lipid metabolites in colorectal cancer development is uncertain. Methods In a case–control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC), we examined associations between pre-diagnostic circulating concentrations of 97 lipid metabolites (acylcarnitines, glycerophospholipids and sphingolipids) and…

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Inflammation and Gut Barrier Function-Related Genes and Colorectal Cancer Risk in Western European Populations

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Gut barrier dysfunction and related inflammation are known to be associated with the development and progression of colorectal cancer (CRC). We investigated associations of 292 single-nucleotide polymorphisms (SNPs) from 27 genes related to endotoxins/lipopolysaccharide (LPS) sensing and tolerance, mucin synthesis, inflammation, and Crohn’s disease with colon and rectal cancer risks. Incident CRC cases (N=1,374; colon=871,…

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Association of Coffee Consumption and Prediagnostic Caffeine Metabolites With Incident Parkinson Disease in a Population-Based Cohort

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Abstract Background and Objectives Inverse associations between caffeine intake and Parkinson disease (PD) have been frequently implicated in human studies. However, no studies have quantified biomarkers of caffeine intake years before PD onset and investigated whether and which caffeine metabolites are related to PD. Methods Associations between self-reported total coffee consumption and future PD risk…

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Nitrosyl-Heme and Heme Iron Intake from Processed Meats in Subjects from the EPIC-Spain Cohort

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background: The consumption of processed meats (PMs) and red meats are linked to the likelihood of developing colorectal cancer. Various theories have been proposed to explain this connection, focusing on nitrosyl-heme and heme iron intake. We hypothesized that differences in nitrosyl-heme and heme iron intakes will be associated with various sociodemographic and lifestyle factors. Methods:…