Territorial and social inequalities in mental distress and self-perceived health among schooled adolescents: a cross-sectional study in central Catalonia and Barcelona

Background Despite being generally considered healthy, adolescence is a crucial period where health behaviours are established, which can impact future well-being. Factors such as social determinants, psychosocial variables, and risk behaviours play significant roles in determining general and mental health, with important gender differences. This article aims to study social inequalities in the prevalence of…

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Association Between Dietary Intake and Blood Concentrations of One-Carbon-Metabolism-Related Nutrients in European Prospective Investigation into Cancer and Nutrition

Background/Objectives: We examined the association between dietary intake and blood concentrations of one-carbon metabolism (OCM)-related nutrients in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: Blood concentrations and dietary intake of the vitamins riboflavin (B2), Pyridoxal 5′-phosphate (PLP and B6), folate (B9), B12, and methionine, concentrations of homocysteine, and dietary intake of betaine,…

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High-dose versus standard-dose influenza vaccine for immunocompromised patients: A systematic review and meta-analysis of randomised clinical trials

Background Immunocompromised patients present a higher risk of severe influenza disease and respond worse to vaccination. Objective We aimed to assess immunogenicity and safety of high-dose vs. standard-dose influenza vaccine in immunocompromised patients. Data source A search was conducted in Medline, Web of Science, Scopus and ClinicalTrials.gov from inception to March 2024 with no other…

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Can serum metabolic signatures inform on the relationship between healthy lifestyle and colon cancer risk?

Background Colon cancer is strongly influenced by lifestyle factors. Sociodemographic factors like sex and socioeconomic position (SEP) might modulate the relationship between lifestyle and colon cancer risk. Metabolomics offers potential to uncover biological mechanisms linking lifestyle and colon cancer. Methods Lifestyle and untargeted metabolomic data were available from a nested case–control study within the European…

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Metabolic profile of biodiverse diets in a healthy European cohort

Background There is increasing evidence that diets characterized by food biodiversity could contribute to health outcomes. Greater dietary species diversity has been linked to reduced gastrointestinal cancer risk and all-cause mortality. However, mechanistic pathways supporting the association between food biodiversity and health are just beginning to be explored. Aim To characterize the metabolic profile associated…

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Nut consumption, linoleic and α-linolenic acid intakes, and genetics: how fatty acid desaturase 1 impacts plasma fatty acids and type 2 diabetes risk in EPIC-InterAct and PREDIMED studies

Background Dietary guidelines recommend replacing saturated fatty acid with unsaturated fats, particularly polyunsaturated fatty acids. Cohort studies do not suggest a clear benefit of higher intake of polyunsaturated fatty acids but, in contrast, higher circulating linoleic acid (LA) levels—reflective of dietary LA intake, are associated with a reduced risk of type 2 diabetes. However, genetic…

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Relationship Between Health-Related Behaviors and Family Quality of Life in Children with Autism Spectrum Disorder

Improving family quality of life (FQoL) of families of children with autism spectrum disorder (ASD) is a key priority in clinical research and practice. Previous studies have suggested that certain health-related behaviors in children with ASD, such as sleep or physical activity, may affect FQoL. However, the relative and independent effects of different health-related behaviors…

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Propuesta de metodología cualitativa para la valoración externa de un proyecto basado en el desarrollo de activos comunitarios

Antecedentes: las acciones de promoción de la salud permiten abordar la injusticia de vivir en lugares no suficientemente dignos para ser habitados. Sin embargo, existen pocas metodologías que describan cómo realizar una evaluación externa en intervenciones de promoción de la salud desde una perspectiva de regeneración comunitaria en estos contextos. Objetivo: presentar un proceso de…

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