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Different diabetes types and pancreatic ductal adenocarcinoma: a Mendelian randomization and pathway/gene-set analysis

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background The associations between different types of diabetes, characterized by distinct pathophysiology and genetic architecture, and pancreatic ductal adenocarcinoma (PDAC) risk are not understood. Methods We investigated associations of genetic susceptibility to type 2 diabetes (T2D), 8 T2D mechanistic clusters, type 1 diabetes (T1D), and maturity-onset diabetes of the young (MODY) with PDAC risk. We…

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Differences in the management and survival of metastatic colorectal cancer in Europe. A population-based study

Artículos Científicos

Background The management regarding metastatic colorectal cancer throughout Europe is not well known. Aims To draw a European comparison of the management and prognosis of metastatic colorectal cancers. Methods Factors associated with chemotherapy administration were identified through logistic regressions. Net survival was estimated and crude probabilities of death related to cancer and other causes using…

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Differences in survival and recurrence of colorectal cancer by stage across population-based European registries

Artículos Científicos, Cáncer, Investigación

European High Resolution Working Group on Colorectum Cancer: Belgium: L Van Eycken, K Henau (Belgian Cancer Registry); Bulgaria: T Grozeva, Z Valerianova, (Bulgarian Cancer Registry); Estonia: K Innos, M Mägi (Estonia Cancer Registry); France: V Bouvier, G Launoy (Calvados Digestive Cancer Registry); Nousbaum JB (Finistère Digestive Cancer Registry); AM Bouvier, V Jooste (Digestive Cancer Registry…

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Diferencias de género en percepciones sobre violencia sexual, igualdad y agresiones sexuales facilitadas por drogas en ocio nocturno

Artículos Científicos

La violencia sexual, incluyendo las agresiones sexuales facilitadas por drogas, es un serio problema cada vez más común en los contextos de ocio nocturno. Este trabajo estudia las actitudes y percepciones de la juventud española en torno a la violencia sexual en dicho ámbito. Los participantes se reclutaron mediante muestreo en bola de nieve. Se…

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Diferencias de género en percepciones sobre violencia sexual, igualdad y agresiones sexuales facilitadas por drogas en ocio nocturno

Igualdad, Investigación, Mujeres EASP

La violencia sexual, incluyendo las agresiones sexuales facilitadas por drogas, es un serio problema cada vez más común en los contextos de ocio nocturno. Este trabajo estudia las actitudes y percepciones de la juventud española en torno a la violencia sexual en dicho ámbito. Los participantes se reclutaron mediante muestreo en bola de nieve. Se…

LupaDetalles

Dietary patterns related to biological mechanisms and survival after breast cancer diagnosis: results from a cohort study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Inflammatory, insulin and oestrogenic pathways have been linked to breast cancer (BC). We aimed to examine the relationship between pre-diagnostic dietary patterns related to these mechanisms and BC survival. Methods The diabetes risk reduction diet (DRRD), inflammatory score of diet (ISD) and oestrogen-related dietary pattern (ERDP) were calculated using dietary data from the European…

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Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality: EPIC cohort study in 9 European countries

Artículos Científicos, Investigación

Dioxins and polychlorinated biphenyls (PCBs) are toxic, endocrine disruptors and persistent chemicals for which the main exposure source is diet due to their bioaccumulation and biomagnification in food chains. Cohort studies in the general populations have reported inconsistent associations between these chemicals in serum/plasma and mortality. Our objective was to study the association between dietary…

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Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and breast cancer risk in 9 European countries

Artículos Científicos

Background Dioxins and polychlorobiphenyls (PCBs) are persistent organic pollutants that have demonstrated endocrine disrupting properties. Several of these chemicals are carcinogenic and positive associations have been suggested with breast cancer risk. In general population, diet represents the main source of exposure. Methods Associations between dietary intake of 17 dioxins and 35 PCBs and breast cancer…

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Dietary intake of trans fatty acids and breast cancer risk in 9 European countries

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted. Methods In the European Prospective Investigation into Cancer and Nutrition (EPIC), we investigated the associations…