LupaDetalles

One-carbon metabolism nutrients and polygenic risk scores in relation to breast cancer risk: a nested case-control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background One-carbon metabolism (1CM) regulates critical processes in carcinogenesis. However, the influence of 1CM-related nutritional and genetic factors on breast cancer (BC) risk remains unclear. Objectives This study aimed to assess the impact of 1CM-related nutrients and genetic variants with BC risk. Methods Case-control study nested within the European Prospective Investigation into Cancer and Nutrition…

LupaDetalles

Effectiveness of natural predators, microbial bioinsecticides, and plant-based bioinsecticides to reduce mosquito-borne disease burden: a systematic review

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Mosquito-borne diseases are a major public health burden given the limited pharmacological options. While the adverse effects of synthetic insecticides are well documented, it is necessary to assess whether environmentally friendly interventions are effective for disease control. Although natural predators, microbial bioinsecticides and plant-based bioinsecticides have gained attention for their specificity and reduced environmental impact,…

LupaDetalles

EPIC4ND—European Prospective Investigation into Cancer and Nutrition follow-up for neurodegenerative diseases

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

The ‘European Prospective Investigation into Cancer and Nutrition’ cohort (EPIC) is a prospective study including ~ 520,000 participants recruited across Europe (1991–2000) with in-depth baseline data on nutritional, lifestyle, medical, and anthropometric variables, and baseline blood samples. Here we introduce EPIC4ND, a case-cohort study within EPIC designed to identify biomarkers predicting a future onset of dementia, Alzheimer’s…

LupaDetalles

Omnivorous and plant-based dietary patterns: a comparative analysis using data-driven and index-based approaches

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background and objective Plant-based diet (PBD) followers are growing worldwide. The aim was to explore the dietary profile of PBDs, taking the omnivorous (OMN) diet as a reference. Methods A cross-sectional study was carried out. A total of 760 participants were included, of whom 161 self-identified as vegan, ovo-lacto-vegetarian, or pesco-vegetarian. Intakes of 175 foods,…

LupaDetalles

Circulating metabolites and fatty acids associated with ultra-processed food consumption: results from the EPIC study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Emerging evidence links consumption of ultra-processed foods (UPF) to higher risks of non-communicable diseases and mortality, but the underlying mechanisms remain unclear. This study aimed to identify molecular signatures of UPF intake in participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Foods were classified into four groups using the Nova system,…

LupaDetalles

Between Safeguard and Constraint: Navigating Patient Autonomy in Protective Laws for Medical Assistance in Dying

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

There has been an increase in the number of jurisdictions legalizing or decriminalizing Medical Assistance in Dying (MAiD). Legal frameworks worldwide strive to balance respect for autonomy with regulatory safeguards that both operationalize voluntary choice and prevent access to MAiD in cases of remediable despair or coerced decision-making. However, the implementation of such an equilibrium…

LupaDetalles

Immune Markers and Risk of Pancreatic Cancer in the European EPIC Cohort

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

The immune system is a major driver in pancreatic cancer development. Several prospective cohort studies have found associations for single immune system-derived proteins such as IL6 or CRP, but results are inconclusive, and Omics-based research is scarce. Hence, we aimed to investigate associations of a comprehensive protein panel with the risk of pancreatic cancer. Within…

LupaDetalles

Mapeo de los activos para la salud y el bienestar del carnaval de Cádiz

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

El carnaval puede relacionarse con la promoción del bienestar, tanto desde las teorías participativas como las socioecológicas y las salutogénicas, centradas en factores que promueven la salud y potencian recursos positivos para afrontar la vida. Quienes participan activamente en el carnaval callejero de Cádiz pueden aportar una perspectiva de interés sobre la promoción de la…

LupaDetalles

Is cancer increasing in young adults in Spain? Incidence trends from the Spanish Network of Cancer Registries (REDECAN)

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Introduction There is growing concern about rising cancer incidence among adults younger than 50 years. This collaborative study within the Spanish Network of Cancer Registries (REDECAN) aimed to examine cancer incidence trends in young adults in Spain. Material and methods This population-based observational study used data from 15 cancer registries. All newly diagnosed cancer cases…

LupaDetalles

Use of population-based cancer registry data to evaluate organized breast cancer screening programmes in Europe by mode of detection: a scoping review

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Organized breast cancer screening programmes are a cornerstone of cancer control policy across Europe. Population-based cancer registries (PBCRs) play a central role in monitoring screening performance, outcomes, and programme quality. However, the extent and methodological approaches of registry-based evaluations across Europe have not been comprehensively synthesized. Following PRISMA-ScR guidelines, we conducted a scoping review of…