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Intake of the Total, Classes, and Subclasses of (Poly)phenols and Breast Cancer Risk: A Prospective Analysis of the EPIC Study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Polyphenols represent the largest and most diverse class of dietary antioxidants. Epidemiological evidence linking specific (poly)phenol classes, such as flavonoids and lignans, to breast cancer (BC) risk remains limited and largely inconclusive in prospective studies. The aim of this study is to examine the association between the intake of total (poly)phenols—and its classes and subclasses—and…

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Associations between dietary exposure to dioxins and polychlorinated biphenyls (PCBs) and Longitudinal changes in weight and waist circumference– an EPIC study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background: Obesity is a growing global health concern. Some evidence suggests that exposure to polychlorinated biphenyls (PCBs) and dioxins, may play a role in weight gain, but human prospective data are limited and have shown inconsistent results. Therefore, this study investigate the association between dietary exposure to dioxins and PCBs and changes in weight and…

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Nuevas formas de reticencia a la vacunación en la era pos-COVID-19: un estudio cualitativo

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objetivo Analizar los argumentos para dudar o rechazar cualquiera de las vacunas contra la COVID-19 y cómo estos discursos han podido modificarse tras la experiencia de la pandemia. Método Se desarrolló un estudio cualitativo exploratorio-descriptivo durante 2021-2022, con cuatro entrevistas semiestructuradas y tres grupos focales mediante muestreo teórico a personas reticentes a las vacunas contra…

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Autoencoders reveal polyunsaturated fatty acids (PUFA)-Related metabolic signature linked to cancer risk

Artículos Científicos, Cáncer, Investigación

Background Metabolomics is a valuable tool for characterising biological mechanisms involved in cancer development, but produces complex datasets with intricate interdependencies. While linear dimension reduction techniques such as principal component analysis (PCA), have proven useful to summarise informative hidden patterns, biological evidence suggests metabolic relationships extend beyond linearity. Non-linear dimension reduction techniques, such as autoencoders…

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Antibody Responses to 11 Fusobacterium Proteins and Colorectal Cancer–Specific and Overall Survival in the EPIC Cohort

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background: Although there is evidence that Fusobacterium spp. in colon tissue is associated with prognosis, less is known about the association between antibody response to antigens expressed by fusobacteria and colorectal cancer–specific mortality. Methods: Antibody responses to 11 Fusobacterium nucleatum (ATCC 25586) antigens were measured in prediagnostic blood for 471 incident colorectal cancer cases (median…

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Drug-Facilitated Sexual Assault Pornography and Sexual Violence While Partying: Cross-Sectional Study

Artículos Científicos, Investigación, Mujeres EASP

Background: Drug-facilitated sexual assaults (DFSAs) in youth partying contexts represent a growing public health concern, affecting approximately half of women and 1 in 4 men. These assaults often occur in environments where alcohol and other psychoactive substances are consumed, leading to impaired consent and increased vulnerability. At the same time, young people are increasingly exposed…

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Breast cancer incidence, by stage at diagnosis, and mortality in 21 European countries in the era of mammography screening: an international population-based study

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background Mammography screening programmes have been widely implemented across European countries over the past 40 years with the main aim to detect breast cancer earlier and thereby reduce breast cancer mortality. This study aimed to analyse and compare changes over time in breast cancer incidence, by stage at diagnosis, and breast cancer mortality across countries…

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Interactions between genetic predisposition to obesity, insulin resistance and type 2 diabetes risk, and food or beverage intake for incident type 2 diabetes: European Prospective Investigation into Cancer and Nutrition (EPIC) InterAct case–cohort study

Cáncer, Investigación

Background Limited evidence exists for effect modification of genetic characteristics on the associations of food consumption and incident type 2 diabetes (T2D). Objectives We aimed to investigate whether the food-T2D association would vary by genetic susceptibility to metabolic traits. Methods We analyzed data from 9542 incident T2D cases and a subcohort of 12,477 participants nested…

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Technology-facilitated sexual violence against women and its health impact: a mixed-methods systematic review

Artículos Científicos, Investigación, Mujeres EASP

Introduction Technology-facilitated sexual violence (TFSV) is a significant public health issue, profoundly impacting women’s health. This systematic review aimed to synthesize evidence on the association between TFSV and mental and physical health in women aged 16 years and older. Methodology Following PRISMA guidelines, a systematic search was conducted across seven databases (CINAHL, Embase, PubMed, PsycINFO,…

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Frameworks encompassing intersectional perspective of artificial intelligence in healthcare. Scoping review

Artículos Científicos, Investigación, Mujeres EASP

Objectives This study systematically evaluates how existing AI frameworks in healthcare address intersectional bias across the AI lifecycle and explores the mitigation strategies proposed. Study design Scoping review. Methods A scoping review was conducted per PRISMA-ScR guidelines, analyzing studies from 2014 to 2024. Searches included MEDLINE (Ovid), PubMed, EMBASE (Ovid), SCOPUS, ESCI, IEEE Xplore, and…