LupaDetalles

Chrono-Nutrition, Chrono-Type, and the Prevalence of Type 2 Diabetes Mellitus in a Cross-Sectional Study from the EuroPean Prospective Investigation into Cancer and Nutrition (EPIC) Study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background: Previous studies have shown that meal timing, poor sleep quality, and chronotype may play a relevant role in the development of type 2 diabetes mellitus (T2DM). However, its relationship with macronutrients by eating occasions has not been explored deeply. Objective: Our aim was to estimate the association between chrono-nutrition, sleep quality, chronotype, and the…

LupaDetalles

Comparing temporal changes and predictors of different types of mental health and socio-emotional wellbeing outcomes during COVID-19: an overlapping panel study of Spanish residents

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objectives Few panel studies have investigated how different types of mental health (MH) and socio-emotional wellbeing (SEW) outcomes have changed during the pandemic and if their burden has been equally distributed at the population-level. We aimed to examine temporal changes in these outcomes and their socio-ecological predictors using panel data. Study design Longitudinal population-based survey…

LupaDetalles

Uno detrás de otro: Factores que influyen en el abandono del ejercicio de la Medicina Familiar y Comunitaria en jóvenes médicos y médicas de familia. Un estudio cualitativo

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

FUNDAMENTOS // Una Atención Primaria fuerte tiene efectos beneficiosos para la salud. El atributo de la misma con mayores beneficios es la longitudinalidad, que requiere de estabilidad laboral para poder producirse. Además, la Atención Primaria se enfrenta a una crisis por el número de jubilaciones que espera. Conseguir la permanencia de los profesionales jóvenes en…

LupaDetalles

Association of body shape phenotypes and body fat distribution indexes with inflammatory biomarkers in the European Prospective Investigation into Cancer and Nutrition (EPIC) and UK Biobank

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background The allometric body shape index (ABSI) and hip index (HI), as well as multi-trait body shape phenotypes, have not yet been compared in their associations with inflammatory markers. The aim of this study was to examine the relationship between novel and traditional anthropometric indexes with inflammation using data from the European Prospective Investigation into…

LupaDetalles

Molecular Mechanisms Linking Genes and Vitamins of the Complex B Related to One-Carbon Metabolism in Breast Cancer: An In Silico Functional Database Study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Carcinogenesis is closely related to the expression, maintenance, and stability of DNA. These processes are regulated by one-carbon metabolism (1CM), which involves several vitamins of the complex B (folate, B2, B6, and B12), whereas alcohol disrupts the cycle due to the inhibition of folate activity. The relationship between nutrients related to 1CM (all aforementioned vitamins…

Detalles

Association between exposure to organophosphate pesticides and cytokine levels in a population of flower workers in Mexico

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The ability of organophosphate pesticides to disturb immune function has been demonstrated by in vivo and in vitro studies, but evidence of such effects on humans remains scarce. To assess the association between organophosphate pesticides exposure and cytokine levels in Mexican flower workers, a cross-sectional study was carried out. A questionnaire was provided to 121…

LupaDetalles

Economic Analysis of Cochlear Implants in Adults With Bilateral Severe-to-Profound Hearing Loss. A Systematic Review of the Literature

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objective To determine the cost-effectiveness or cost-utility of cochlear implants (CI) in adults with severe to profound bilateral hearing loss. Databases Reviewed PubMed (Medline), The Cochrane Library, Embase via Elsevier, EBSCOhost CINAHL, and Scopus. Methods The study included adult participants with severe to profound bilateral neurosensory hearing loss. The analysis encompassed quality of life improvements,…

LupaDetalles

For, against, and beyond: healthcare professionals’ positions on Medical Assistance in Dying in Spain

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background In 2021, Spain became the first Southern European country to grant and provide the right to euthanasia and medically assisted suicide. According to the law, the State has the obligation to ensure its access through the health services, which means that healthcare professionals’ participation is crucial. Nevertheless, its implementation has been uneven. Our research…

LupaDetalles

Circulating free insulin-like growth factor-I and prostate cancer: a case-control study nested in the European prospective investigation into cancer and nutrition

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Circulating total insulin-like growth factor-I (IGF-I) is an established risk factor for prostate cancer. However, only a small proportion of circulating IGF-I is free or readily dissociable from IGF-binding proteins (its bioavailable form), and few studies have investigated the association of circulating free IGF-I with prostate cancer risk. Methods We analyzed data from 767…

LupaDetalles

Biomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Introduction Personalised prevention aims to delay or avoid disease occurrence, progression, and recurrence of disease through the adoption of targeted interventions that consider the individual biological, including genetic data, environmental and behavioural characteristics, as well as the socio-cultural context. This protocol summarises the main features of a rapid scoping review to show the research landscape…