Ver todoArtículos CientíficosPublicaciones EASP
Ordenar por fechaOrdenar por nombre
DescendenteAscendente
LupaDetalles

Changes in molecular biomarkers of neurotoxicity in newborns following prenatal exposure to organophosphate compounds

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The rising incidence of neurodevelopmental disorders has been associated with early-life exposure to environmental factors, particularly neurotoxicants like organophosphate compounds (OPCs), which can impact brain development and function. This study examined the relationship between prenatal exposure to OPCs and molecular biomarkers of neurotoxicity in cord blood from 398 mother-child pairs in the GENEIDA birth cohort…

LupaDetalles

Changes in lifestyle and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Introduction: We investigated the impact of changes in lifestyle habits on colorectal cancer (CRC) risk in a multi-country European cohort. Methods: We used baseline and follow-up questionnaire data from the EPIC cohort to assess changes in lifestyle habits and their associations with CRC development. We calculated a healthy lifestyle index (HLI) score based on smoking…

LupaDetalles

Changes in Caregiver Personal Support Networks: Gender Differences and Effects on Health (CUIDAR-SE Study)

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Technological changes have led to important advances in medical diagnoses and treatments that prolong the informal care process. Support from the personal network of informal caregivers is an undervalued resource and the changes that have occurred over time are unknown. The aim of this study was to analyze the changes in personal network support among…

LupaDetalles

Challenges for Economic Evaluations of Advanced Therapy Medicinal Products: A Systematic Review

Artículos Científicos, Investigación, Mujeres EASP

Objectives Advanced therapy medicinal products (ATMPs) are drugs for human use for the treatment of chronic, degenerative, or life-threatening diseases that are based on genes, tissues, or cells. This article aimed to identify and critically review published economic analyses of ATMPs. Methods A systematic review of economic analyses of ATMPs was undertaken. Study characteristics, design,…

LupaDetalles

Centenary Personality: Are There Psychological Resources that Distinguish Centenarians?

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The number of centenarians is increasing year by year. Considering that happier people are likely to live longer, we asked ourselves whether healthy centenarians share psychological resources or positive personality characteristics that have enabled them to face traumatic situations and the challenges life more successfully. To our knowledge this is an issue that has not…

EnlaceLupaDetalles

Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study

Artículos Científicos

Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). Measurements of waist circumference, triglycerides, high-density lipoprotein cholesterol (HDLC), systolic and diastolic blood pressure, glycated hemoglobin as components of MetS definition, and plasma total neopterin…

LupaDetalles

Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Micro- and nanoplastics (MNPs) are increasingly recognized as emerging contaminants of concern for human health. Their small size, diverse composition, and reactive surface enable interactions with biological barriers and cellular systems. This comprehensive narrative review synthesizes and critically evaluates current evidence on the mechanistic effects of MNPs in humans and experimental models. Systemic mechanisms, including…

LupaDetalles

Causal effects of lifetime smoking on breast and colorectal cancer risk: Mendelian randomization study

Artículos Científicos

Background: Observational evidence has shown that smoking is a risk factor for breast and colorectal cancer. We used Mendelian randomization (MR) to examine causal associations between smoking and risks of breast and colorectal cancer. Methods: Genome-wide association study summary data were used to identify genetic variants associated with lifetime amount of smoking (n=126 variants) and…

LupaDetalles

Caregiving and Caregiver Health 1 Year into the COVID-19 Pandemic (CUIDAR-SE Study): A Gender Analysis

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The COVID-19 pandemic has highlighted the importance of informal care and shown that women continue to shoulder the brunt of responsibilities in this area. In this study, we analyzed differences in caregiving and self-perceived health in a group of informal male and female caregivers 1 year into the COVID-19 pandemic. We performed a cross-sectional survey…

LupaDetalles

Cardiovascular diseases among diffuse large B-cell lymphoma long-term survivors in Asia: a multistate model study

Artículos Científicos, Cáncer, Investigación

Background We modeled the clinical course of a cohort of diffuse large B-cell lymphoma (DLBCL) patients with no prior cardiovascular diseases (CVDs) using a multistate modeling framework. Patients and methods Data on 2600 patients with DLBCL diagnosed between 2000 and 2018 and had received chemotherapy with or without radiotherapy were obtained from a population-wide electronic…