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Mediterranean diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort

Artículos Científicos

Background: The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: Over half…

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Medicina basada en las «existencias» o soporte ético para las decisiones difíciles

Artículos Científicos

La pandemia por coronavirus está provocando una crisis de salud pública mundial sobre la que aún desconocemos gran parte de sus manifestaciones clínicas, comportamiento epidemiológico y abordaje terapéutico. También sus consecuencias de tipo social y económico son impredecibles a medio y largo plazo. España está siendo uno de los países más afectados, tanto en incidencia…

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Mediational Occupational Risk Factors Pertaining to Work Ability According to Age, Gender and Professional Job Type

Artículos Científicos

The predictive value of work ability for several health and occupational outcomes is well known. Maintaining the ability to work of all employees has become an important topic in research although some evidence suggests that some groups of workers need greater attention than others. Healthcare workers (x¯ = 54.46 ± 5.64 years) attending routine occupational…

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Mediation analysis of the alcohol‐postmenopausal breast cancer relationship by sex hormones in the EPIC Cohort

Artículos Científicos

Alcohol consumption is associated with higher risk of breast cancer (BC); however, the biological mechanisms underlying this association are not fully elucidated, particularly the extent to which this relationship is mediated by sex hormone levels. Circulating concentrations of estradiol, testosterone, their free fractions and sex‐hormone binding globulin (SHBG), were examined in 430 incident BC cases…

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Mediating role of lifestyle behaviours in the association between education and cancer: results from the European Prospective Investigation into Cancer and Nutrition

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background: Many studies have shown that socioeconomic position (SEP) is associated with the incidence of malignant tumors at different sites. This study aims to estimate the association between educational level (as proxy for SEP) and cancer incidence and to understand if the observed associations might be partially explained by lifestyle behaviors. Methods: The analyses were…

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Mediating effect of soluble B-cell activation immune markers on the association between anthropometric and lifestyle factors and lymphoma development

Artículos Científicos

Sustained B-cell activation is an important mechanism contributing to B-cell lymphoma (BCL). We aimed to validate four previously reported B-cell activation markers predictive of BCL risk (sCD23, sCD27, sCD30, and CXCL13) and to examine their possible mediating effects on the association between anthropometric and lifestyle factors and major BCL subtypes. Pre-diagnostic serum levels were measured…

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Mechanisms Considering Public Investment in Pricing and Reimbursement Decisions of Medicines and Other Health Technologies: A Scoping Review

Artículos Científicos

Background Pricing and reimbursement (P&R) systems do not normally use public investments in research and development (R&D) as criteria when negotiating the prices and reimbursement of health technologies. Objective The objective was to find mechanisms that consider public investment in R&D when negotiating P&R or obtaining a fair return on this public investment Methods We…

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Mecanismo de acción de la anticoncepción de urgencia con levonorgestrel: ¿cuál es la evidencia?

Artículos Científicos

Carta al director de la profesora de la EASP, María del Mar García Calvente sobre los efectos del levonorgestrel en la anticoncepción de emergencia Sr. Director: Agradecemos el interés mostrado por Alegre del Rey et al. por nuestro editorial Anticoncepción de urgencia y objeción de conciencia: un debate sin cerrar1. Afirman estos autores que existe…

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Meat Intake Is Associated with a Higher Risk of Ulcerative Colitis in a Large European Prospective Cohort Studyø

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Abstract Background and Aims We aimed to investigate the association between protein intake and risk of inflammatory bowel disease [IBD] in the European Prospective Investigation into Cancer and Nutrition. Methods A total of 413 593 participants from eight European countries were included. Dietary data were collected at baseline from validated food frequency questionnaires. Dietary data…