Work, household, and leisure-time physical activity and risk of mortality in the EPIC-Spain cohort

Objective Large-scale longitudinal data on the association of domain-specific physical activity (PA) and mortality is limited. Our objective was to evaluate the association of work, household (HPA), and leisure time PA (LTPA) with overall and cause-specific mortality in the EPIC-Spain study. Methods 38,379 participants (62.4% women), 30–65 years old, and free of chronic disease at baseline…

Intensive alcohol consumption by adolescents in Southern Spain: The importance of friendship

Background There has been an increase in intensive alcohol drinking by Spanish adolescents since the 1990s, especially among the females, but there has been limited exploration of this phenomenon. The objective of this study was to analyse the discourses of Spanish adolescents on their drinking behaviour at contextual, relational, and personal levels. Methods A qualitative…

Planificación anticipada de decisiones en Salud Mental. Guía de apoyo para profesionales y personas usuarias de los servicios de salud mental

Salvaguardar el derecho a la toma de decisiones de forma autónoma y con libertad es una obligación de los servicios y profesionales en todos los ámbitos de la atención socio-sanitaria. En el caso de las personas con trastorno mental, es un imperativo legal, formulado en la Convención de Derechos de las Personas con Discapacidad. Garantizar el derecho de…

Envejecimiento activo. Un marco político ante la revolución de la longevidad

El Centro Internacional para la longevidad de Brasil (ILC-Brasil) es un think-tank independiente con sede en Rio de Janeiro, inaugurado en 2012. Su misión es promulgar ideas y orientaciones políticas para abordar el envejecimiento de la población basándose en la investigación y la experiencia a nivel internacional con vistas a promover el envejecimiento activo. ILC…

The Influence of Hormonal Factors on the Risk of Developing Cervical Cancer and Pre-Cancer: Results from the EPIC Cohort

Background In addition to HPV, high parity and hormonal contraceptives have been associated with cervical cancer (CC). However, most of the evidence comes from retrospective case-control studies. The aim of this study is to prospectively evaluate associations between hormonal factors and risk of developing cervical intraepithelial neoplasia grade 3 (CIN3)/carcinoma in situ (CIS) and invasive…

Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study

Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). Measurements of waist circumference, triglycerides, high-density lipoprotein cholesterol (HDLC), systolic and diastolic blood pressure, glycated hemoglobin as components of MetS definition, and plasma total neopterin…

Was access to health care easy for immigrants in Spain? The perspectives of health personnel in Catalonia and Andalusia

Until April 2012, all Spanish citizens were entitled to health care and policies had been developed at national and regional level to remove potential barriers of access, however, evidence suggested problems of access for immigrants. In order to identify factors affecting immigrants’ access to health care, we conducted a qualitative study based on individual interviews…

Systematic reviews on neurodevelopmental and neurodegenerative disorders linked to pesticide exposure: Methodological features and impact on risk assessment

Background Epidemiological data are not currently used in the risk assessment of chemical substances in a systematic and consistent manner. However, systematic reviews (SRs) could be useful for risk assessment as they appraise and synthesize the best epidemiological knowledge available. Objectives To conduct a comprehensive literature search of SRs pertaining to pesticide exposure and various…

Plasma carotenoids, vitamin C, tocopherols, and retinol and the risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition cohor

Background: Carotenoids and vitamin C are thought to be associated with reduced cancer risk because of their antioxidative capacity. Objective: This study evaluated the associations of plasma carotenoid, retinol, tocopherol, and vitamin C concentrations and risk of breast cancer. Design: In a nested case-control study within the European Prospective Investigation into Cancer and Nutrition cohort,…