Boletines serie infografías cáncer

Factors influencing the diagnostic basis in pancreatic cancer. A study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Background and aims Substantial differences have been reported in risk estimates for etiologic factors of pancreatic cancer among subjects with different degrees of diagnostic certainty. The aim of the study was to assess the influence of some personal and social characteristics on the diagnostic basis in individuals with pancreatic cancer. Methods We analyzed 393 participants…

Intake of total, classes, and subclasses of (poly)phenols and risk of lymphoid neoplasms: a prospective analysis in the EPIC cohort

Background Existing epidemiological evidence regarding the potential role of (poly)phenol intake in lymphoma development is limited. Methods We investigated the associations between the intake of total and individual classes and subclasses of (poly)phenols and the risk of lymphoma, including main frequent subtypes in the EPIC cohort using multivariable-adjusted Cox proportional hazards models. Results During a…

Survival trends and cure rates of hematological neoplasms in the Spanish pediatric population

Hematological neoplasms (HN) were the first cause of death in children aged 5–9 years in Spain. The aim of this registry-based study is to provide a detailed overview of the survival of HN in the Spanish pediatric population. All pediatric HN cases included were classified according to the International Classification for Childhood Cancer. Flexible parametric…

Quantifying the environmental and food biodiversity impacts of ultra-processed foods: evidence from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Objective:While associations of ultra-processed food (UPF) consumption with adverse health outcomes are accruing, its environmental and food biodiversity impacts remain underexplored. This study examines associations between UPF consumption and dietary greenhouse gas emissions (GHGe), land use and food biodiversity. Design:Prospective cohort study. Linear mixed models estimated associations between UPF intake (g/d and kcal/d) and GHGe…

Development of a blood-based lipidomic fat quality score for the risk of ischemic stroke

Introduction: Poor-quality diets promote ischemic stroke. Red blood cell fatty acids (RBC-FAs) are objective, long-term biomarkers of diet. In a case-control study nested in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain, we developed a blood-based lipidomic fat quality (LFQ) score considering pre-defined RBC-FA diet-related biomarkers, and examined whether LFQ score relates to the…

Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis

Background It is currently unknown whether plant-based dietary patterns influence disease progression to multimorbidity after an initial non-communicable disease, and whether the associated risk of multimorbidity varies with age. This study aimed to investigate associations of plant-based diets with the risk of multimorbidity, defined as the co-occurrence of at least two chronic diseases in an…

Biodiverse diets present co-benefits for greenhouse gas emissions, land use, mortality rates and nutritional adequacy in Europe

Dietary diversity is vital for public health nutrition, yet the co-benefits of increasing dietary species richness (DSR) on human and environmental health remain unassessed. Here we explore associations between DSR and greenhouse gas emissions, land use, nutrient adequacy and mortality rates among European Investigation into Cancer and Nutrition (EPIC) study participants. Total DSR was positively…

Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study

Background Thyroid-stimulating hormone (TSH) and thyroid hormones (free triiodothyronine [fT3] and free thyroxine [fT4]) may influence cancer outcomes, but evidence for ovarian cancer is limited. Methods We conducted a nested case–control study comparing 578 epithelial ovarian cancer (EOC) cases with matched controls within the European Prospective Investigation into Cancer and Nutrition (EPIC). To examine associations…

Young Men’s Communication Needs for the Human Papillomavirus (HPV) Vaccine: A Cross-Cultural, Qualitative Analysis in Scotland, Spain, and the USA

Background Globally, human papillomavirus (HPV) vaccine uptake rates have declined within a wider context of vaccine hesitancy. Gender-neutral vaccine programmes are increasing and recommended for the prevention of cervical, anogenital, and oropharyngeal cancers affecting both women and men. To address the problem of suboptimal HPV uptake rates for boys and men, we aimed to understand…

Body mass index and breast cancer risk among postmenopausal women with and without cardiometabolic diseases: Findings from two prospective cohort studies in Europe

Background Adiposity, measured by body mass index (BMI), is a known risk factor for postmenopausal breast cancer. However, whether the association of BMI with breast cancer risk differs among women with and without cardiovascular diseases (CVDs) or type 2 diabetes (T2D) is uncertain. Methods This study used individual participant data from the European Prospective Investigation…