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Quantifying the environmental and food biodiversity impacts of ultra-processed foods: evidence from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Objective:While associations of ultra-processed food (UPF) consumption with adverse health outcomes are accruing, its environmental and food biodiversity impacts remain underexplored. This study examines associations between UPF consumption and dietary greenhouse gas emissions (GHGe), land use and food biodiversity. Design:Prospective cohort study. Linear mixed models estimated associations between UPF intake (g/d and kcal/d) and GHGe…

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Development of a blood-based lipidomic fat quality score for the risk of ischemic stroke

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Introduction: Poor-quality diets promote ischemic stroke. Red blood cell fatty acids (RBC-FAs) are objective, long-term biomarkers of diet. In a case-control study nested in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain, we developed a blood-based lipidomic fat quality (LFQ) score considering pre-defined RBC-FA diet-related biomarkers, and examined whether LFQ score relates to the…

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Diseño y validación de un cuestionario para medir la fotoprotección en los niños y sus familias (Cuestionario Fotoprotección Sulayr)

Artículos Científicos

Antecedentes y objetivo La prevención primaria es el único modo de disminuir la incidencia del cáncer de piel. Con ese objetivo diseñamos y evaluamos la viabilidad, validez y reproducibilidad de un cuestionario sobre conductas fotoprotectoras y sus variables asociadas en la población infantil y en sus familias. Material y métodos Tras revisar la literatura, un…

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Mechanisms Considering Public Investment in Pricing and Reimbursement Decisions of Medicines and Other Health Technologies: A Scoping Review

Artículos Científicos

Background Pricing and reimbursement (P&R) systems do not normally use public investments in research and development (R&D) as criteria when negotiating the prices and reimbursement of health technologies. Objective The objective was to find mechanisms that consider public investment in R&D when negotiating P&R or obtaining a fair return on this public investment Methods We…

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Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background It is currently unknown whether plant-based dietary patterns influence disease progression to multimorbidity after an initial non-communicable disease, and whether the associated risk of multimorbidity varies with age. This study aimed to investigate associations of plant-based diets with the risk of multimorbidity, defined as the co-occurrence of at least two chronic diseases in an…

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Biodiverse diets present co-benefits for greenhouse gas emissions, land use, mortality rates and nutritional adequacy in Europe

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Dietary diversity is vital for public health nutrition, yet the co-benefits of increasing dietary species richness (DSR) on human and environmental health remain unassessed. Here we explore associations between DSR and greenhouse gas emissions, land use, nutrient adequacy and mortality rates among European Investigation into Cancer and Nutrition (EPIC) study participants. Total DSR was positively…

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Comparative clinical outcomes of acenocoumarol versus direct oral anticoagulants (DOACs) and warfarin in patients with atrial fibrillation: real-world-evidence (SIESTA-A study)

Artículos Científicos

Objective: The aim of this study was to evaluate the effectiveness and safety of direct oral anticoagulants (DOACs: dabigatran, rivaroxaban, apixaban and edoxaban) and warfarin versus acenocoumarol in patients with atrial fibrillation under real-world clinical practice conditions. Methods: This was a retrospective, real-world data-based study. The data source was the Andalusian Population Health Database. The…

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Gestational exposure to organophosphate pesticides and maternal urine metabolomic profile in the GENEIDA birth cohort

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Early developmental exposure to organophosphate (OP) pesticides has been linked to adverse health effects, though the underlying molecular pathways remain unclear. This study examined urinary metabolomic profiles of 387 pregnant women in their first and third trimesters using UPLC-MS/MS to identify metabolic disruptions associated with OPs exposure measured via dialkyl phosphate (DAPs) metabolites, including total,…

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Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Thyroid-stimulating hormone (TSH) and thyroid hormones (free triiodothyronine [fT3] and free thyroxine [fT4]) may influence cancer outcomes, but evidence for ovarian cancer is limited. Methods We conducted a nested case–control study comparing 578 epithelial ovarian cancer (EOC) cases with matched controls within the European Prospective Investigation into Cancer and Nutrition (EPIC). To examine associations…

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Young Men’s Communication Needs for the Human Papillomavirus (HPV) Vaccine: A Cross-Cultural, Qualitative Analysis in Scotland, Spain, and the USA

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Globally, human papillomavirus (HPV) vaccine uptake rates have declined within a wider context of vaccine hesitancy. Gender-neutral vaccine programmes are increasing and recommended for the prevention of cervical, anogenital, and oropharyngeal cancers affecting both women and men. To address the problem of suboptimal HPV uptake rates for boys and men, we aimed to understand…