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Desde la necesidad de información a la estrategia de búsqueda, pasando por el formato PICO

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Dado el crecimiento exponencial de la producción científica, resulta imprescindible que profesionales y la comunidad universitaria dispongan de herramientas y competencias para hacer eficiente la búsqueda de información relevante. Las necesidades de información requieren ser trabajadas y transformadas en preguntas susceptibles de ser contestadas, para lo que resulta de gran utilidad la adaptación al formato…

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Reducción gradual de dosis frente a deprescripción abrupta de antipsicóticos en pacientes con demencia: una revisión sistemática

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objetivo: Sintetizar la evidencia disponible sobre la reducción gradual de la dosis de antipsicóticos o su deprescripción abrupta en personas mayores con demencia. Métodos: Revisión sistemática de estudios de intervención. Se consultaron las bases de datos PubMed, Embase, Web of Science-Core Collection, Cochrane Library, Scopus, MEDLINE (Ovid) y PsycINFO. Se incluyeron estudios (ensayos aleatorios o…

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Territorial and social inequalities in mental distress and self-perceived health among schooled adolescents: a cross-sectional study in central Catalonia and Barcelona

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background Despite being generally considered healthy, adolescence is a crucial period where health behaviours are established, which can impact future well-being. Factors such as social determinants, psychosocial variables, and risk behaviours play significant roles in determining general and mental health, with important gender differences. This article aims to study social inequalities in the prevalence of…

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Association Between Dietary Intake and Blood Concentrations of One-Carbon-Metabolism-Related Nutrients in European Prospective Investigation into Cancer and Nutrition

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background/Objectives: We examined the association between dietary intake and blood concentrations of one-carbon metabolism (OCM)-related nutrients in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: Blood concentrations and dietary intake of the vitamins riboflavin (B2), Pyridoxal 5′-phosphate (PLP and B6), folate (B9), B12, and methionine, concentrations of homocysteine, and dietary intake of betaine,…

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Risk of a second primary cancer after breast cancer in Southern Spain: a population-based study over 3 decades

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Abstract Objective To estimate the risk of developing a second primary cancer (SPC) among women diagnosed with breast cancer in Granada, Spain. Study design This population-based observational cohort study utilized data from the Granada Cancer Registry. We included all women aged 15 and above diagnosed with malignant breast cancer from 1985 to 2019. Main outcome…

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High-dose versus standard-dose influenza vaccine for immunocompromised patients: A systematic review and meta-analysis of randomised clinical trials

Artículos Científicos, Investigación

Background Immunocompromised patients present a higher risk of severe influenza disease and respond worse to vaccination. Objective We aimed to assess immunogenicity and safety of high-dose vs. standard-dose influenza vaccine in immunocompromised patients. Data source A search was conducted in Medline, Web of Science, Scopus and ClinicalTrials.gov from inception to March 2024 with no other…

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Can serum metabolic signatures inform on the relationship between healthy lifestyle and colon cancer risk?

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Colon cancer is strongly influenced by lifestyle factors. Sociodemographic factors like sex and socioeconomic position (SEP) might modulate the relationship between lifestyle and colon cancer risk. Metabolomics offers potential to uncover biological mechanisms linking lifestyle and colon cancer. Methods Lifestyle and untargeted metabolomic data were available from a nested case–control study within the European…

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Revisión sistemática sobre el uso de peces para el control vectorial de las enfermedades transmitidas por mosquitos

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

FUNDAMENTOS // Se estima que un 80% de la población mundial está en riesgo de contraer una enfermedad de transmisión vectorial, siendo los mosquitos los responsables de una mayor carga de enfermedad. Dado que el control biológico es una opción más natural que otras intervenciones disponibles y que el uso de peces está muy extendido,…

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Metabolic profile of biodiverse diets in a healthy European cohort

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background There is increasing evidence that diets characterized by food biodiversity could contribute to health outcomes. Greater dietary species diversity has been linked to reduced gastrointestinal cancer risk and all-cause mortality. However, mechanistic pathways supporting the association between food biodiversity and health are just beginning to be explored. Aim To characterize the metabolic profile associated…

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Nut consumption, linoleic and α-linolenic acid intakes, and genetics: how fatty acid desaturase 1 impacts plasma fatty acids and type 2 diabetes risk in EPIC-InterAct and PREDIMED studies

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background Dietary guidelines recommend replacing saturated fatty acid with unsaturated fats, particularly polyunsaturated fatty acids. Cohort studies do not suggest a clear benefit of higher intake of polyunsaturated fatty acids but, in contrast, higher circulating linoleic acid (LA) levels—reflective of dietary LA intake, are associated with a reduced risk of type 2 diabetes. However, genetic…