Understanding and reframing clinical errors through just culture: protocol for the DECIDE mixed-methods study in Spanish healthcare and community contexts

Introduction Patient safety culture plays a crucial role in reducing clinical errors. By improving healthcare professionals’ and patients’ understanding of human fallibility and error attribution, patient care can be enhanced, fostering greater engagement from both groups. A Just Culture approach, which balances accountability and learning from errors, is a key factor in fostering this safety…

Gender inequalities of caregiver mental health and burden in the three years post COVID-19 (CUIDAR-SE Study)

Background The COVID-19 pandemic has significantly impacted progress towards the Sustainable Development Goals (SDGs), particularly SDG 3 (ensuring healthy lives and well-being) and SDG 5 (achieving gender equality), especially for caregivers. Increased demand for informal caregiving has disproportionately impacted caregivers, worsening mental health challenges. Intense burden reinforces traditional gender norms and exacerbates health inequities, linking…

Biomarkers for Personalised Primary or Secondary Prevention in Cardiovascular Diseases: A Rapid Scoping Review

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality globally. Early detection and personalised prevention strategies are crucial for reducing the burden of CVD. The use of biomarkers plays a pivotal role in identifying individuals at risk and facilitating timely interventions. This rapid scoping review aims to identify and evaluate current research on…

Factors influencing the diagnostic basis in pancreatic cancer. A study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Background and aims Substantial differences have been reported in risk estimates for etiologic factors of pancreatic cancer among subjects with different degrees of diagnostic certainty. The aim of the study was to assess the influence of some personal and social characteristics on the diagnostic basis in individuals with pancreatic cancer. Methods We analyzed 393 participants…

Intake of total, classes, and subclasses of (poly)phenols and risk of lymphoid neoplasms: a prospective analysis in the EPIC cohort

Background Existing epidemiological evidence regarding the potential role of (poly)phenol intake in lymphoma development is limited. Methods We investigated the associations between the intake of total and individual classes and subclasses of (poly)phenols and the risk of lymphoma, including main frequent subtypes in the EPIC cohort using multivariable-adjusted Cox proportional hazards models. Results During a…

Walkability, Right to the City and Right to Health: pathways toward equity and justice – a systematic mixed-methods review

This paper explores the intersection of walkability, the Right to Health and the Right to the City, with a particular emphasis on equitable access in rapidly urbanizing environments. Urbanization exacerbates challenges to health inequities, particularly for vulnerable populations with limited access to walkable, health-promoting spaces. Through a systematic mixed-methods literature review, we analyze how walkability…

Quantifying the environmental and food biodiversity impacts of ultra-processed foods: evidence from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Objective:While associations of ultra-processed food (UPF) consumption with adverse health outcomes are accruing, its environmental and food biodiversity impacts remain underexplored. This study examines associations between UPF consumption and dietary greenhouse gas emissions (GHGe), land use and food biodiversity. Design:Prospective cohort study. Linear mixed models estimated associations between UPF intake (g/d and kcal/d) and GHGe…

Development of a blood-based lipidomic fat quality score for the risk of ischemic stroke

Introduction: Poor-quality diets promote ischemic stroke. Red blood cell fatty acids (RBC-FAs) are objective, long-term biomarkers of diet. In a case-control study nested in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain, we developed a blood-based lipidomic fat quality (LFQ) score considering pre-defined RBC-FA diet-related biomarkers, and examined whether LFQ score relates to the…

Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis

Background It is currently unknown whether plant-based dietary patterns influence disease progression to multimorbidity after an initial non-communicable disease, and whether the associated risk of multimorbidity varies with age. This study aimed to investigate associations of plant-based diets with the risk of multimorbidity, defined as the co-occurrence of at least two chronic diseases in an…

Biodiverse diets present co-benefits for greenhouse gas emissions, land use, mortality rates and nutritional adequacy in Europe

Dietary diversity is vital for public health nutrition, yet the co-benefits of increasing dietary species richness (DSR) on human and environmental health remain unassessed. Here we explore associations between DSR and greenhouse gas emissions, land use, nutrient adequacy and mortality rates among European Investigation into Cancer and Nutrition (EPIC) study participants. Total DSR was positively…