LupaDetalles

Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts

Cáncer, Igualdad, Investigación, Mujeres EASP

Background Amino acid metabolism is dysregulated in colorectal cancer patients; however, it is not clear whether pre-diagnostic levels of amino acids are associated with subsequent risk of colorectal cancer. We investigated circulating levels of amino acids in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) and UK Biobank…

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Relationship between Sexual Violence and the Health of Spanish Women—A National Population-Based Study

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background: Health consequences are likely to be different when sexual violence is analysed independently from other types of violence. It is also likely that different health consequences will result in the cases of partner or ex-partner sexual violence, non-partner sexual violence and sexual harassment. Methods: This study is based on the 2019 Macro-survey of Violence…

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Prediagnostic serum calcium concentrations and risk of colorectal cancer development in 2 large European prospective cohorts

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Higher dietary calcium consumption is associated with lower colorectal cancer (CRC) risk. However, little data are available on the association between circulating calcium concentrations and CRC risk. Objectives To explore the association between circulating calcium concentrations and CRC risk using data from 2 large European prospective cohort studies. Methods Conditional logistic regression models were used to calculate multivariable-adjusted ORs and 95%…

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A step towards harmonising human biomonitoring study setup on European level: Materials provided and lessons learnt in HBM4EU

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Internal exposure of the human body to potentially harmful chemical substances can be assessed by Human Biomonitoring (HBM). HBM can be used to generate conclusive data that may provide an overview of exposure levels in entire or specific population groups. This knowledge can promote the understanding of potential risks of the substances of interest or help monitoring…

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Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Iron is an essential micronutrient with differing intake patterns and metabolism between men and women. Epidemiologic evidence on the association of dietary iron and its heme and non-heme components with colorectal cancer (CRC) development is inconclusive. Methods We examined baseline dietary questionnaire-assessed intakes of total, heme, and non-heme iron and CRC risk in the…

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Dietary patterns related to biological mechanisms and survival after breast cancer diagnosis: results from a cohort study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Inflammatory, insulin and oestrogenic pathways have been linked to breast cancer (BC). We aimed to examine the relationship between pre-diagnostic dietary patterns related to these mechanisms and BC survival. Methods The diabetes risk reduction diet (DRRD), inflammatory score of diet (ISD) and oestrogen-related dietary pattern (ERDP) were calculated using dietary data from the European…

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Comparative effects of different types of exercise on health-related quality of life during and after active cancer treatment: A systematic review and network meta-analysis

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background The positive influence of most types of exercise has been reported repeatedly, but what the most effective exercise approaches are for improving health-related quality of life (HRQoL) in people with cancer remains unknown. The aim of this systematic review and network meta-analysis (NMA) was to synthesize the evidence from intervention studies to assess the…

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Pre-diagnostic Serum Glyceraldehyde-Derived Advanced Glycation End Products and Mortality Among Colorectal Cancer Patients

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Glyceraldehyde-derived advanced glycation end products (glycer-AGEs) could contribute to colorectal cancer development and progression due to their pro-oxidative and pro-inflammatory properties. However, the association of glycer-AGEs with mortality after colorectal cancer diagnosis has not been previously investigated. Circulating glycer-AGEs were measured by competitive ELISA. Multivariable Cox proportional hazards models were used to calculate hazard ratios…

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Do patients with type 2 diabetes have impaired hip bone microstructure? A study using 3D modeling of hip dual-energy X-ray absorptiometry

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Aim: Patients with type 2 diabetes (T2DM) have more risk of bone fractures. However, areal bone mineral density (aBMD) by conventional dual-energy x-ray absorptiometry (DXA) is not useful for identifying this risk. This study aims to evaluate 3D-DXA parameters determining the cortical and trabecular compartments in patients with T2DM compared to non-diabetic subjects and to…

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Evidencia sobre la externalización de los servicios de diálisis: Una revisión de alcance

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Introducción La enfermedad renal crónica representa un importante problema de salud, tanto por su elevada incidencia y prevalencia, como por su importante morbimortalidad y coste socioeconómico. Objetivo Comparar la efectividad y consecuencias económicas de la diálisis concertada frente a la diálisis hospitalaria. Metodología Revisión de alcance, para lo cual se consultaron diferentes bases de datos,…