Value of concerted and hospital hemodialysis through a multi-criteria decision analysis-Valor de la hemodiálisis concertada y la hospitalaria mediante un análisis de decisión multicriterio

Objetivo Evaluar el valor de la prestación de servicios de diálisis concertada frente a la hospitalaria para el tratamiento de la enfermedad renal crónica en España mediante la metodología de análisis de decisión multicriterio. Método Se utilizó el marco de evaluación EVIDEM (Evidence and Value: Impact on Decision Making) para el cálculo del valor estimado…

Pre-diagnostic circulating resistin concentrations and mortality among individuals with colorectal cancer: Results from the European Prospective Investigation into Cancer and Nutrition study

Resistin is a protein involved in inflammation and angiogenesis processes and may play a role in the progression of colorectal cancer (CRC). However, it remains unclear whether resistin is associated with increased mortality after CRC diagnosis. We examined pre-diagnostic serum resistin concentrations in relation to CRC-specific and all-cause mortality among 1343 incident CRC cases from…

Lifestyle changes in middle age and risk of cancer: evidence from the European Prospective Investigation into Cancer and Nutrition

In this study, we aimed to provide novel evidence on the impact of changing lifestyle habits on cancer risk. In the EPIC cohort, 295,865 middle-aged participants returned a lifestyle questionnaire at baseline and during follow-up. At both timepoints, we calculated a healthy lifestyle index (HLI) score based on cigarette smoking, alcohol consumption, body mass index…

Assessment of an intervention for preventing pediatric overweight and obesity through the World Café technique: A qualitative study

Purpose To evaluate the self-reported perspectives of participants involved in the Previene Cádiz intervention for preventing pediatric overweight and obesity. Design and methods This qualitative study collected information through the World Café technique. A purposive sample of 40 participants was used, of which 14 were schoolchildren, 12 were teachers, and 14 were parent volunteers. The…

Relationship between exposure to parabens and benzophenones and prostate cancer risk in the EPIC-Spain cohort

The etiology of prostate cancer is not fully elucidated. Among environmental risk factors, endocrine-disrupting chemicals (EDCs) deserve special mention, as they alter metabolic pathways involved in hormone-dependent cancers. Epidemiological evidence assessing the carcinogenicity of EDCs is scarce. The aim of this study was to analyze the relationship between exposure to parabens and benzophenones and prostate…

Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment

Background: Central nervous system (CNS) neoplasms are highly frequent solid tumours in children and adolescents. While some studies have shown a rise in their incidence in Europe, others have not. Survival remains limited. We addressed two questions about these tumours in Spain: (1) Is incidence increasing? and (2) Has survival improved? Methods: This population-based study…

Había una vez un lugar donde aprendimos a escuchar. The Other Front line_voces por la justicia social

Las respuestas de los gobiernos a la pandemia de la COVID-19 generaron una nueva ola de desigualdades sociales para las comunidades de todo el mundo que vivían en circunstancias injustas (1). Los confinamientos y las medidas sanitarias pasaron por alto las condiciones de vivienda, las transiciones a la escolarización virtual, ignorando los hogares y las…

Dietary index based on the Food Standards Agency nutrient profiling system and risk of Crohn’s disease and ulcerative colitis

Background Nutri-score is now widely available in food packages in Europe. Aim To study the overall nutritional quality of the diet in relation to risks of Crohn’s disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort Methods We collected dietary data at baseline from validated food frequency…

International Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts

PURPOSE There is strong evidence that leisure-time physical activity is protective against postmenopausal breast cancer risk but the association with premenopausal breast cancer is less clear. The purpose of this study was to examine the association of physical activity with the risk of developing premenopausal breast cancer. METHODS We pooled individual-level data on self-reported leisure-time…

Breast cancer risk for the joint exposure to metals and metalloids in women: Results from the EPIC-Spain cohort

Environmental factors play a role in breast cancer development. While metals and metalloids (MMs) include some carcinogens, their association with breast cancer depends on the element studied. Most studies focus on individual MMs, but the combined effects of metal mixtures remain unclear. The aim of this study was to analyze the relationship between the joint…