LupaDetalles

Development of a blood-based lipidomic fat quality score for the risk of ischemic stroke

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Introduction: Poor-quality diets promote ischemic stroke. Red blood cell fatty acids (RBC-FAs) are objective, long-term biomarkers of diet. In a case-control study nested in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain, we developed a blood-based lipidomic fat quality (LFQ) score considering pre-defined RBC-FA diet-related biomarkers, and examined whether LFQ score relates to the…

LupaDetalles

Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background It is currently unknown whether plant-based dietary patterns influence disease progression to multimorbidity after an initial non-communicable disease, and whether the associated risk of multimorbidity varies with age. This study aimed to investigate associations of plant-based diets with the risk of multimorbidity, defined as the co-occurrence of at least two chronic diseases in an…

LupaDetalles

Biodiverse diets present co-benefits for greenhouse gas emissions, land use, mortality rates and nutritional adequacy in Europe

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Dietary diversity is vital for public health nutrition, yet the co-benefits of increasing dietary species richness (DSR) on human and environmental health remain unassessed. Here we explore associations between DSR and greenhouse gas emissions, land use, nutrient adequacy and mortality rates among European Investigation into Cancer and Nutrition (EPIC) study participants. Total DSR was positively…

LupaDetalles

Gestational exposure to organophosphate pesticides and maternal urine metabolomic profile in the GENEIDA birth cohort

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Early developmental exposure to organophosphate (OP) pesticides has been linked to adverse health effects, though the underlying molecular pathways remain unclear. This study examined urinary metabolomic profiles of 387 pregnant women in their first and third trimesters using UPLC-MS/MS to identify metabolic disruptions associated with OPs exposure measured via dialkyl phosphate (DAPs) metabolites, including total,…

LupaDetalles

Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Thyroid-stimulating hormone (TSH) and thyroid hormones (free triiodothyronine [fT3] and free thyroxine [fT4]) may influence cancer outcomes, but evidence for ovarian cancer is limited. Methods We conducted a nested case–control study comparing 578 epithelial ovarian cancer (EOC) cases with matched controls within the European Prospective Investigation into Cancer and Nutrition (EPIC). To examine associations…

LupaDetalles

Young Men’s Communication Needs for the Human Papillomavirus (HPV) Vaccine: A Cross-Cultural, Qualitative Analysis in Scotland, Spain, and the USA

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Globally, human papillomavirus (HPV) vaccine uptake rates have declined within a wider context of vaccine hesitancy. Gender-neutral vaccine programmes are increasing and recommended for the prevention of cervical, anogenital, and oropharyngeal cancers affecting both women and men. To address the problem of suboptimal HPV uptake rates for boys and men, we aimed to understand…

LupaDetalles

Perceived acceptability of sexual violence against women in Spain and associated factors

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Sexual violence (SV) is considered a major public health problem affecting the lifelong health, opportunities, and wellbeing of hundreds of millions of people.1 Most recent estimates from the World Health Organization (WHO) indicate that 27 % of females aged over 15 experience physical and/or SV at the hands of their partner, whilst 6 % suffer SV from…

LupaDetalles

Estimated exposure of flame-retardants in Spanish toddlers: a modelling approach

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Flame retardants (FRs) are chemicals used to reduce the flammability of materials and are commonly found in consumer products such as furniture and electronics. These substances can migrate from products (e.g., furniture foam and electronic devices) into indoor environments such as air and dust and may pose risk to human health by direct exposure. Some…

LupaDetalles

Associations of internal persistent organic pollutant levels with sex hormones: An analysis by sex and menopausal status in a Spanish cohort

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The aim of this study was to investigate associations between human exposure to persistent organic pollutants and sex hormone levels. The study population (n = 253) was a subsample of GraMo adult cohort, recruited in 2003–2004 in two hospitals from Granada, Spain. Exposure was estimated by analyzing samples of adipose tissue (3 organochlorine pesticides and…

LupaDetalles

Body mass index and breast cancer risk among postmenopausal women with and without cardiometabolic diseases: Findings from two prospective cohort studies in Europe

Cáncer, Igualdad, Investigación, Mujeres EASP

Background Adiposity, measured by body mass index (BMI), is a known risk factor for postmenopausal breast cancer. However, whether the association of BMI with breast cancer risk differs among women with and without cardiovascular diseases (CVDs) or type 2 diabetes (T2D) is uncertain. Methods This study used individual participant data from the European Prospective Investigation…