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Is cancer increasing in young adults in Spain? Incidence trends from the Spanish Network of Cancer Registries (REDECAN)

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Introduction There is growing concern about rising cancer incidence among adults younger than 50 years. This collaborative study within the Spanish Network of Cancer Registries (REDECAN) aimed to examine cancer incidence trends in young adults in Spain. Material and methods This population-based observational study used data from 15 cancer registries. All newly diagnosed cancer cases…

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Use of population-based cancer registry data to evaluate organized breast cancer screening programmes in Europe by mode of detection: a scoping review

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Organized breast cancer screening programmes are a cornerstone of cancer control policy across Europe. Population-based cancer registries (PBCRs) play a central role in monitoring screening performance, outcomes, and programme quality. However, the extent and methodological approaches of registry-based evaluations across Europe have not been comprehensively synthesized. Following PRISMA-ScR guidelines, we conducted a scoping review of…

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Assessing Organizational Readiness for Just Culture in Health Care

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background: A Just Culture promotes fairness, accountability, and psychological safety in response to adverse events. Despite growing interest in its implementation, Spanish-speaking health care systems lack validated tools to assess organizational readiness. Objective: To develop and validate a Spanish-language instrument [Organizational Readiness for Just Accountability Scale (ORJA-S)] to assess health care professionals’ attitudes that reflect…

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Una década de progreso en la eliminación de la hepatitis C: desde el Plan Estratégico Nacional a la Inteligencia Artificial

Artículos Científicos, Investigación

Introducción El virus de la hepatitis C (VHC) es un agente patógeno trans- mitido por vía parenteral que produce enfermedad hepática como consecuencia de la perpetuación del da˜no inflamato- rio en el hígado. A partir de la respuesta inmunitaria del huésped frente a los hepatocitos infectados, se inicia el desarrollo de fibrosis hepática y su…

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Association between lifestyle and risk of early-onset cancer: Evidence from the European Prospective Investigation into Cancer and Nutrition and the UK Biobank

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background The incidence of early-onset cancers (EOCs), defined as cancers diagnosed before 50 years of age, has risen globally over the past three decades. The association between modifiable lifestyle factors and EOC risk has been poorly investigated. Methods Participants enrolled before age 50 in EPIC (39,459 men; 110,991 women) and the UK Biobank (52,188 men;…

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Educational disparities in the association of protein diversity and type 2 diabetes: a multi-country population-based prospective case-cohort study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Purpose To investigate socio-economic disparities in the association between dietary diversity and type 2 diabetes (T2D). Methods Prospective secondary analysis study of 10,363 incident cases of T2D over 12 years and a random sub-cohort of 13,937 individuals in the EPIC-InterAct case-cohort study. We used baseline self-reported diet data (1991–1998) to construct scores for diversity between food…

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Barreras y desafíos a la coordinación asistencial en el Sistema Nacional de Salud. Informe SESPAS 2026

Artículos Científicos, Investigación

La coordinación es vital para el buen desempeño de los sistemas de salud. Este trabajo analiza las barreras y los desafíos de la coordinación asistencial en el Sistema Nacional de Salud (SNS), profundizando en sus causas-raíz, para que el diagnóstico de la situación aporte claves de avance. Se analizan, en primer lugar, los problemas de…

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Variabilidad en la toma de decisiones médicas en pacientes críticos durante la pandemia COVID-19 en España

Artículos Científicos, Investigación

Introducción La investigación sobre decisión clínica en Unidades de Cuidados Intensivos (UCI) durante la pandemia COVID-19 es limitada. Los objetivos del estudio son cuantificar la variabilidad en las decisiones de médicos de UCI en España y evaluar su asociación a factores contextuales. Métodos Estudio experimental cuali-cuantitativo intrasujeto con viñetas, con manipulación de factores contextuales (hora…

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The Stress-Buffering Effect of Social Support on Socio-Economic Disparities in Mental Health among Cancer Survivors

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background: Low socio-economic status (SES) is considered a major chronic stressor and is frequently associated with worse mental health among cancer survivors. We investigated the extent to which social support could mitigate the negative impact of low SES on the mental health of individuals with a history of cancer. Method: Participants were cancer survivors identified…

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Polygenic scores for risk of pancreatic ductal adenocarcinoma: evaluation of novel and published models

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Polygenic risk scores (PRSs) may enhance risk stratification for pancreatic ductal adenocarcinoma (PDAC), but existing models vary widely in design, predictive performance, and cross-ancestry transferability. We developed genome-wide PRSs using Bayesian methods (LDpred2 and PRS-CS) and p value thresholding (PRSice-2) and systematically evaluated these alongside 13 published PRSs to identify models with robust predictive performance…