Walkability, Right to the City and Right to Health: pathways toward equity and justice – a systematic mixed-methods review

This paper explores the intersection of walkability, the Right to Health and the Right to the City, with a particular emphasis on equitable access in rapidly urbanizing environments. Urbanization exacerbates challenges to health inequities, particularly for vulnerable populations with limited access to walkable, health-promoting spaces. Through a systematic mixed-methods literature review, we analyze how walkability…

Quantifying the environmental and food biodiversity impacts of ultra-processed foods: evidence from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Objective:While associations of ultra-processed food (UPF) consumption with adverse health outcomes are accruing, its environmental and food biodiversity impacts remain underexplored. This study examines associations between UPF consumption and dietary greenhouse gas emissions (GHGe), land use and food biodiversity. Design:Prospective cohort study. Linear mixed models estimated associations between UPF intake (g/d and kcal/d) and GHGe…

Development of a blood-based lipidomic fat quality score for the risk of ischemic stroke

Introduction: Poor-quality diets promote ischemic stroke. Red blood cell fatty acids (RBC-FAs) are objective, long-term biomarkers of diet. In a case-control study nested in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain, we developed a blood-based lipidomic fat quality (LFQ) score considering pre-defined RBC-FA diet-related biomarkers, and examined whether LFQ score relates to the…

Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis

Background It is currently unknown whether plant-based dietary patterns influence disease progression to multimorbidity after an initial non-communicable disease, and whether the associated risk of multimorbidity varies with age. This study aimed to investigate associations of plant-based diets with the risk of multimorbidity, defined as the co-occurrence of at least two chronic diseases in an…

Biodiverse diets present co-benefits for greenhouse gas emissions, land use, mortality rates and nutritional adequacy in Europe

Dietary diversity is vital for public health nutrition, yet the co-benefits of increasing dietary species richness (DSR) on human and environmental health remain unassessed. Here we explore associations between DSR and greenhouse gas emissions, land use, nutrient adequacy and mortality rates among European Investigation into Cancer and Nutrition (EPIC) study participants. Total DSR was positively…

Gestational exposure to organophosphate pesticides and maternal urine metabolomic profile in the GENEIDA birth cohort

Early developmental exposure to organophosphate (OP) pesticides has been linked to adverse health effects, though the underlying molecular pathways remain unclear. This study examined urinary metabolomic profiles of 387 pregnant women in their first and third trimesters using UPLC-MS/MS to identify metabolic disruptions associated with OPs exposure measured via dialkyl phosphate (DAPs) metabolites, including total,…

Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study

Background Thyroid-stimulating hormone (TSH) and thyroid hormones (free triiodothyronine [fT3] and free thyroxine [fT4]) may influence cancer outcomes, but evidence for ovarian cancer is limited. Methods We conducted a nested case–control study comparing 578 epithelial ovarian cancer (EOC) cases with matched controls within the European Prospective Investigation into Cancer and Nutrition (EPIC). To examine associations…

Young Men’s Communication Needs for the Human Papillomavirus (HPV) Vaccine: A Cross-Cultural, Qualitative Analysis in Scotland, Spain, and the USA

Background Globally, human papillomavirus (HPV) vaccine uptake rates have declined within a wider context of vaccine hesitancy. Gender-neutral vaccine programmes are increasing and recommended for the prevention of cervical, anogenital, and oropharyngeal cancers affecting both women and men. To address the problem of suboptimal HPV uptake rates for boys and men, we aimed to understand…

Perceived acceptability of sexual violence against women in Spain and associated factors

Sexual violence (SV) is considered a major public health problem affecting the lifelong health, opportunities, and wellbeing of hundreds of millions of people.1 Most recent estimates from the World Health Organization (WHO) indicate that 27 % of females aged over 15 experience physical and/or SV at the hands of their partner, whilst 6 % suffer SV from…

Estimated exposure of flame-retardants in Spanish toddlers: a modelling approach

Flame retardants (FRs) are chemicals used to reduce the flammability of materials and are commonly found in consumer products such as furniture and electronics. These substances can migrate from products (e.g., furniture foam and electronic devices) into indoor environments such as air and dust and may pose risk to human health by direct exposure. Some…