Hematological neoplasms (HN) were the first cause of death in children aged 5–9 years in Spain. The aim of this registry-based study is to provide a detailed overview of the survival of HN in the Spanish pediatric population. All pediatric HN cases included were classified according to the International Classification for Childhood Cancer. Flexible parametric…
This paper explores the intersection of walkability, the Right to Health and the Right to the City, with a particular emphasis on equitable access in rapidly urbanizing environments. Urbanization exacerbates challenges to health inequities, particularly for vulnerable populations with limited access to walkable, health-promoting spaces. Through a systematic mixed-methods literature review, we analyze how walkability…
Background Epilepsy drug treatments fail in 25–30 % of patients, leading to drug resistance. Temporal lobe epilepsy is the most prevalent subtype associated with drug resistance. Classical drug discovery is a long and extremely costly process with a high failure rate in clinical trials. Drug repurposing is a more cost- and time-effective strategy. Hence, the main…
Objective:While associations of ultra-processed food (UPF) consumption with adverse health outcomes are accruing, its environmental and food biodiversity impacts remain underexplored. This study examines associations between UPF consumption and dietary greenhouse gas emissions (GHGe), land use and food biodiversity. Design:Prospective cohort study. Linear mixed models estimated associations between UPF intake (g/d and kcal/d) and GHGe…
Introduction: Poor-quality diets promote ischemic stroke. Red blood cell fatty acids (RBC-FAs) are objective, long-term biomarkers of diet. In a case-control study nested in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain, we developed a blood-based lipidomic fat quality (LFQ) score considering pre-defined RBC-FA diet-related biomarkers, and examined whether LFQ score relates to the…
Antecedentes y objetivo La prevención primaria es el único modo de disminuir la incidencia del cáncer de piel. Con ese objetivo diseñamos y evaluamos la viabilidad, validez y reproducibilidad de un cuestionario sobre conductas fotoprotectoras y sus variables asociadas en la población infantil y en sus familias. Material y métodos Tras revisar la literatura, un…
Background Pricing and reimbursement (P&R) systems do not normally use public investments in research and development (R&D) as criteria when negotiating the prices and reimbursement of health technologies. Objective The objective was to find mechanisms that consider public investment in R&D when negotiating P&R or obtaining a fair return on this public investment Methods We…
Background It is currently unknown whether plant-based dietary patterns influence disease progression to multimorbidity after an initial non-communicable disease, and whether the associated risk of multimorbidity varies with age. This study aimed to investigate associations of plant-based diets with the risk of multimorbidity, defined as the co-occurrence of at least two chronic diseases in an…
Dietary diversity is vital for public health nutrition, yet the co-benefits of increasing dietary species richness (DSR) on human and environmental health remain unassessed. Here we explore associations between DSR and greenhouse gas emissions, land use, nutrient adequacy and mortality rates among European Investigation into Cancer and Nutrition (EPIC) study participants. Total DSR was positively…
Objective: The aim of this study was to evaluate the effectiveness and safety of direct oral anticoagulants (DOACs: dabigatran, rivaroxaban, apixaban and edoxaban) and warfarin versus acenocoumarol in patients with atrial fibrillation under real-world clinical practice conditions. Methods: This was a retrospective, real-world data-based study. The data source was the Andalusian Population Health Database. The…
