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A Framework for Considering the Role of the Public Sector in R&D of Health Technology

Artículos Científicos

The development of health technologies involves complex, costly, and risky investments, with significant contributions from both public and private sectors. Recent EU pharmaceutical directives propose transparency on public funding to aid pricing negotiations and affordability. However, questions remain regarding how public investments should be measured and their influence on pricing and reimbursement (P&R) decisions. In…

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Economic Evaluation of Treatment With Trastuzumab Deruxtecan for HER2-Low Advanced or Metastatic Breast Cancer in Previously Treated Patients

Artículos Científicos

Objectives This study evaluates the efficiency and budgetary impact of trastuzumab deruxtecan (T-DXd) compared with standard therapy in previously treated HER2-low advanced or metastatic breast cancer, from the perspective of the Spanish National Health System. Methods A partitioned survival model was developed using data from the DESTINY-BREAST04 trial. Health outcomes were measured in quality-adjusted life…

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Perceived acceptability of sexual violence against women in Spain and associated factors

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Sexual violence (SV) is considered a major public health problem affecting the lifelong health, opportunities, and wellbeing of hundreds of millions of people.1 Most recent estimates from the World Health Organization (WHO) indicate that 27 % of females aged over 15 experience physical and/or SV at the hands of their partner, whilst 6 % suffer SV from…

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Estimated exposure of flame-retardants in Spanish toddlers: a modelling approach

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Flame retardants (FRs) are chemicals used to reduce the flammability of materials and are commonly found in consumer products such as furniture and electronics. These substances can migrate from products (e.g., furniture foam and electronic devices) into indoor environments such as air and dust and may pose risk to human health by direct exposure. Some…

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Ética y Salud Pública

Publicaciones EASP

Este texto forma parte de los resultados de investigación de la red ESPACyOS. Ética de la Salud Pública, financiada por la Agencia Estatal de Investigación (RED2022- 134551-T) y con la  colaboración de FECYT-Ministerio de Ciencia, Innovación y Universidades (FCT-24-19978) y POyETICAS (PID2023-148517NB-100). Primera edición, 2025 © Maite Cruz, Joaquín Hortal y Àngel Puyol, 2025 ©…

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Associations of internal persistent organic pollutant levels with sex hormones: An analysis by sex and menopausal status in a Spanish cohort

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The aim of this study was to investigate associations between human exposure to persistent organic pollutants and sex hormone levels. The study population (n = 253) was a subsample of GraMo adult cohort, recruited in 2003–2004 in two hospitals from Granada, Spain. Exposure was estimated by analyzing samples of adipose tissue (3 organochlorine pesticides and…

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Body mass index and breast cancer risk among postmenopausal women with and without cardiometabolic diseases: Findings from two prospective cohort studies in Europe

Cáncer, Igualdad, Investigación, Mujeres EASP

Background Adiposity, measured by body mass index (BMI), is a known risk factor for postmenopausal breast cancer. However, whether the association of BMI with breast cancer risk differs among women with and without cardiovascular diseases (CVDs) or type 2 diabetes (T2D) is uncertain. Methods This study used individual participant data from the European Prospective Investigation…

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Desde la necesidad de información a la estrategia de búsqueda, pasando por el formato PICO

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Dado el crecimiento exponencial de la producción científica, resulta imprescindible que profesionales y la comunidad universitaria dispongan de herramientas y competencias para hacer eficiente la búsqueda de información relevante. Las necesidades de información requieren ser trabajadas y transformadas en preguntas susceptibles de ser contestadas, para lo que resulta de gran utilidad la adaptación al formato…

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Reducción gradual de dosis frente a deprescripción abrupta de antipsicóticos en pacientes con demencia: una revisión sistemática

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objetivo: Sintetizar la evidencia disponible sobre la reducción gradual de la dosis de antipsicóticos o su deprescripción abrupta en personas mayores con demencia. Métodos: Revisión sistemática de estudios de intervención. Se consultaron las bases de datos PubMed, Embase, Web of Science-Core Collection, Cochrane Library, Scopus, MEDLINE (Ovid) y PsycINFO. Se incluyeron estudios (ensayos aleatorios o…

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Territorial and social inequalities in mental distress and self-perceived health among schooled adolescents: a cross-sectional study in central Catalonia and Barcelona

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background Despite being generally considered healthy, adolescence is a crucial period where health behaviours are established, which can impact future well-being. Factors such as social determinants, psychosocial variables, and risk behaviours play significant roles in determining general and mental health, with important gender differences. This article aims to study social inequalities in the prevalence of…