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A method for sensitivity analysis to assess the effects of measurement error in multiple exposure variables using external validation data

Artículos Científicos

Background: Measurement error in self-reported dietary intakes is known to bias the association between dietary intake and a health outcome of interest such as risk of a disease. The association can be distorted further by mismeasured confounders, leading to invalid results and conclusions. It is, however, difficult to adjust for the bias in the association when there is…

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Evaluación de una estrategia formativa entre iguales en fibromialgia. Un análisis de género

Artículos Científicos

La fibromialgia es una enfermedad crónica altamente feminizada que requiere mayor autonomía y autoeficiencia en el manejo de los cuidados. Objetivo: evaluar, desde una perspectiva de género, la estrategia formativa de pacientes con fibromialgia de la Escuela de Pacientes, basada en la formación “entre iguales”. Método: estudio cuantitativo, con diseño cuasiexperimental pretest- postest, con 600 participantes con fibromialgia. Se…

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Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations

Artículos Científicos

Identifying genetic variants with pleiotropic associations can uncover common pathways influencing multiple cancers. We took a two-staged approach to conduct genome-wide association studies for lung, ovary, breast, prostate and colorectal cancer from the GAME-ON/GECCO Network (61,851 cases, 61,820 controls) to identify pleiotropic loci. Findings were replicated in independent association studies (55,789 cases, 330,490 controls). We…

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Analysis of the experience of Cuban physicians in a Brazilian metropolis in accordance with the Paideia Method

Artículos Científicos

]We had hoped that the Mais Médicos Program (More Doctors Program) would have generated several changes and reflections in each municipality in which it was deployed. In order to observe those changes, we sought to analyze the experience of Cuban physicians in the Mais Médicos program from an actor-centered perspective, based on the Paideia Method…

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Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population

Artículos Científicos

We previously identified osteopontin (OPN) as a promising marker for the early detection of hepatocellular carcinoma (HCC). In this study, we investigated the association between prediagnostic circulating OPN levels and HCC incidence in a large population-based cohort. A nested case–control study was conducted within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. During…

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Análisis de las buenas prácticas de participación ciudadana en las unidades de gestión clínica del Servicio Andaluz de Salud

Artículos Científicos

Objetivo Conocer buenas prácticas de participación ciudadana en las unidades de gestión clínica (UGC) del Servicio Andaluz de Salud (SAS) y explorar factores percibidos por profesionales de UGC del SAS que pueden influir en la existencia y la distribución de buenas prácticas de participación ciudadana. Método Estudio con metodología mixta realizado en Andalucía en dos…

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Sweet-beverage consumption and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Artículos Científicos

Background: The consumption of sweet beverages has been associated with greater risk of type 2 diabetes and obesity, which may be involved in the development of pancreatic cancer. Therefore, it has been hypothesized that sweet beverages may increase pancreatic cancer risk as well. Objective: We examined the association between sweet-beverage consumption (including total, sugar-sweetened, and…

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Associations of maternal o,p′-DDT and p,p′-DDE levels with birth outcomes in a Bolivian cohort

Artículos Científicos

This study examined the potential association of maternal serum levels of o,p′-DDT and p,p′-DDE with gestation time and with anthropometric measurements and thyroid-stimulating hormone (TSH) levels of newborns in a Bolivian birth cohort. Two hundred mothers were consecutively recruited between January and March 2013 at the “Hospital de la Mujer Dr. Percy Boland” in Santa…