On the use of the healthy lifestyle index to investigate specific disease outcomes

The healthy lifestyle index (HLI), defined as the unweighted sum of individual lifestyle components, was used to investigate the combined role of lifestyle factors on health-related outcomes. We introduced weighted outcome-specific versions of the HLI, where individual lifestyle components were weighted according to their associations with disease outcomes. Within the European Prospective Investigation into Cancer…

Economic Analysis of Cochlear Implants in Adults With Bilateral Severe-to-Profound Hearing Loss. A Systematic Review of the Literature

Objective To determine the cost-effectiveness or cost-utility of cochlear implants (CI) in adults with severe to profound bilateral hearing loss. Databases Reviewed PubMed (Medline), The Cochrane Library, Embase via Elsevier, EBSCOhost CINAHL, and Scopus. Methods The study included adult participants with severe to profound bilateral neurosensory hearing loss. The analysis encompassed quality of life improvements,…

For, against, and beyond: healthcare professionals’ positions on Medical Assistance in Dying in Spain

Background In 2021, Spain became the first Southern European country to grant and provide the right to euthanasia and medically assisted suicide. According to the law, the State has the obligation to ensure its access through the health services, which means that healthcare professionals’ participation is crucial. Nevertheless, its implementation has been uneven. Our research…

¿Qué necesitamos para «hacer comunitaria»? Veinticinco medidas prácticas para gerencias y equipos de atención primaria

Objetivo Identificar y matizar qué medidas organizativas prácticas promoverían el desarrollo de las actividades comunitarias de nivel 2 (educación para la salud grupal con orientación comunitaria) y nivel 3 (acción comunitaria) en Atención Primaria (AP) desde la perspectiva de profesionales de medicina con formación y experiencia en este ámbito. Método Estudio exploratorio, descriptivo y transversal…

Nitrosyl-heme and Heme Iron Intake from Processed Meats and Risk of Colorectal Cancer in the EPIC-Spain Cohort

Background: The International Agency for Research on Cancer classified processed meats (PM) as “carcinogenic” and red meat as “probably carcinogenic” for humans. The possible relationship between colorectal cancer risk and the mechanisms involved in the carcinogenesis of PMs have not been established yet. Nitrosyl-heme and heme iron have been proposed as potential-related compounds. The aim…

Circulating free insulin-like growth factor-I and prostate cancer: a case-control study nested in the European prospective investigation into cancer and nutrition

Background Circulating total insulin-like growth factor-I (IGF-I) is an established risk factor for prostate cancer. However, only a small proportion of circulating IGF-I is free or readily dissociable from IGF-binding proteins (its bioavailable form), and few studies have investigated the association of circulating free IGF-I with prostate cancer risk. Methods We analyzed data from 767…

Biomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews

Introduction Personalised prevention aims to delay or avoid disease occurrence, progression, and recurrence of disease through the adoption of targeted interventions that consider the individual biological, including genetic data, environmental and behavioural characteristics, as well as the socio-cultural context. This protocol summarises the main features of a rapid scoping review to show the research landscape…

Systematic review of healthcare interventions for reducing gender-based violence impact on the mental health of women with disabilities

Purpose Women with disabilities are more exposed to violence. The health sector has a key role in all three levels of prevention of violence against women. The objective of this paper was to review the interventions for preventing gender-based violence and reducing its impact on the mental health of women with any form of disability.…

A Th2-type immune response and low-grade systemic inflammatory reaction as potential immunotoxic effects in intensive agriculture farmers exposed to pesticides

Pesticides are chemicals widely used in agriculture to keep crops healthy and prevent them from being destroyed by pests, thus contributing to a sustainable food and feed production. However, long-term exposure to these compounds may be harmful to human health as they can affect the function of various organs systems, including the immune system. There…

The COVID-19 Pandemic as a Public Health Teacher—the Lessons We Must Learn

Since 5th May 2023 COVID-19 is not considered a Public Health Emergency of International Concern (PHEIC), rather “an established and ongoing health issue” [1]. This was a moment to celebrate achievements, like the dedication of healthcare workers but also to reflect on the mistakes made [1]. Many COVID-19 deaths are still reported to the World…