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Pre-diagnostic circulating resistin concentrations and mortality among individuals with colorectal cancer: Results from the European Prospective Investigation into Cancer and Nutrition study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Resistin is a protein involved in inflammation and angiogenesis processes and may play a role in the progression of colorectal cancer (CRC). However, it remains unclear whether resistin is associated with increased mortality after CRC diagnosis. We examined pre-diagnostic serum resistin concentrations in relation to CRC-specific and all-cause mortality among 1343 incident CRC cases from…

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Lifestyle changes in middle age and risk of cancer: evidence from the European Prospective Investigation into Cancer and Nutrition

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

In this study, we aimed to provide novel evidence on the impact of changing lifestyle habits on cancer risk. In the EPIC cohort, 295,865 middle-aged participants returned a lifestyle questionnaire at baseline and during follow-up. At both timepoints, we calculated a healthy lifestyle index (HLI) score based on cigarette smoking, alcohol consumption, body mass index…

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Assessment of an intervention for preventing pediatric overweight and obesity through the World Café technique: A qualitative study

Artículos Científicos, Investigación, Mujeres EASP

Purpose To evaluate the self-reported perspectives of participants involved in the Previene Cádiz intervention for preventing pediatric overweight and obesity. Design and methods This qualitative study collected information through the World Café technique. A purposive sample of 40 participants was used, of which 14 were schoolchildren, 12 were teachers, and 14 were parent volunteers. The…

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Economic evaluation of adjuvant therapy with osimertinib in patients with early-stage non–small cell lung cancer and mutated EGFR

Artículos Científicos, Investigación

Purpose The ADAURA trial demonstrated the superiority of osimertinib over a placebo with regard to disease-free survival, showing it to be indicated as an adjuvant therapy for treatment of non–small cell lung cancer with mutated epidermal growth factor receptor (EGFR). The aim of the present study was to conduct a cost-utility analysis and an analysis…

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Relationship between exposure to parabens and benzophenones and prostate cancer risk in the EPIC-Spain cohort

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

The etiology of prostate cancer is not fully elucidated. Among environmental risk factors, endocrine-disrupting chemicals (EDCs) deserve special mention, as they alter metabolic pathways involved in hormone-dependent cancers. Epidemiological evidence assessing the carcinogenicity of EDCs is scarce. The aim of this study was to analyze the relationship between exposure to parabens and benzophenones and prostate…

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Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background: Central nervous system (CNS) neoplasms are highly frequent solid tumours in children and adolescents. While some studies have shown a rise in their incidence in Europe, others have not. Survival remains limited. We addressed two questions about these tumours in Spain: (1) Is incidence increasing? and (2) Has survival improved? Methods: This population-based study…

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Había una vez un lugar donde aprendimos a escuchar. The Other Front line_voces por la justicia social

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Las respuestas de los gobiernos a la pandemia de la COVID-19 generaron una nueva ola de desigualdades sociales para las comunidades de todo el mundo que vivían en circunstancias injustas (1). Los confinamientos y las medidas sanitarias pasaron por alto las condiciones de vivienda, las transiciones a la escolarización virtual, ignorando los hogares y las…

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Use of the Therapy App Prescinde for Increasing Adherence to Smoking Cessation Treatment

Artículos Científicos

Tobacco use poses major health risks and is a major contributor to causes of death worldwide. Mobile phone-based cessation apps for this substance are gaining popularity, often used as a component of traditional interventions. This study aimed to analyze adherence to an intervention using a mobile phone application (App-therapy Prescinde (v1)) as a function of…

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The Efficiency of Increased HCV Testing and Treatment Strategies in Spain to Achieve Elimination Goals

Artículos Científicos

Background In 2015, Spain launched a national eradication strategy for hepatitis C virus (HCV), resulting in the highest treatment rate in Europe and substantial reductions in HCV prevalence. However, to achieve the goal of HCV elimination, it is necessary to scale-up the diagnosis, treatment, and management of HCV infection. Objective Our aim was to assess…

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Dietary index based on the Food Standards Agency nutrient profiling system and risk of Crohn’s disease and ulcerative colitis

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background Nutri-score is now widely available in food packages in Europe. Aim To study the overall nutritional quality of the diet in relation to risks of Crohn’s disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort Methods We collected dietary data at baseline from validated food frequency…