Regresión logística en salud pública
Esta obra de 2000 está pensada para un lector del campo de la salud, pero también puede ser de interés para investigadores y estudiantes de estadística y de ciencias sociales. [wpdm_file id=94]
Regional Versus Centralized Hta: Implications for the Assessment of Cancer Drugs
Different jurisdictions organize their health technology assessment (HTA) capacity in different ways. In theory, a centralized approach offers the potential to pool the scarce resources devoted to HTA and national recommendations can be issued to encourage a uniform development of services across the whole country. On the other hand, a regional approach could help in…
Reflexiones sobre cómo evaluar y mejorar la respuesta a la pandemia de COVID-19
La pandemia de COVID-19ha afectado de manera particularmente intensa a España, pese a su nivel de desarrollo y la elogiada solidez de su Sistema Nacional de Salud. Para comprender qué ha pasado e identificar cómo mejorar la respuesta creemos imprescindible una evaluación independiente multidisciplinaria de la esfera sanitaria, política y socioeconómica. En este trabajo proponemos…
Reducción gradual de dosis frente a deprescripción abrupta de antipsicóticos en pacientes con demencia: una revisión sistemática
Objetivo: Sintetizar la evidencia disponible sobre la reducción gradual de la dosis de antipsicóticos o su deprescripción abrupta en personas mayores con demencia. Métodos: Revisión sistemática de estudios de intervención. Se consultaron las bases de datos PubMed, Embase, Web of Science-Core Collection, Cochrane Library, Scopus, MEDLINE (Ovid) y PsycINFO. Se incluyeron estudios (ensayos aleatorios o…
Redes personales de apoyo y cuidado informal: ¿diferencias por sexo y territorio? (estudio CUIDAR-SE II)
Objetivo Comparar la composición y la funcionalidad de apoyo social de redes personales de personas cuidadoras de Granada y Gipuzkoa en función del sexo y la provincia. Método Estudio transversal con metodología de análisis de redes personales. Se seleccionó una muestra de 66 personas cuidadoras segmentada por sexo en cada provincia. Se recogieron variables de…
Red blood cell fatty acids and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Background: A growing body of evidence suggests that alterations of dietary fatty acid (FA) profiles are associated with colorectal cancer (CRC) risk. However, data from large-scale epidemiological studies using circulating FA measurements to objectively assess individual FA and FA categories are scarce. Methods: To investigate the association between red blood cell (RBC) membrane FAs and…
Recognizing a Heart Attack: Patients’ Knowledge of Cardiovascular Risk Factors and Its Relation to Prehospital Decision Delay in Acute Coronary Syndrome
In acute coronary syndromes (ACSs), longer decision delay – the time patients wait before seeking medical attention after symptoms have started – increases the risk of complications and death. However, many patients wait much longer than recommended and research is needed investigating how patient decision delay can be reduced. In a cross-sectional study of 120…
Recesión bibliográfica: Health technology assessment and health policy today: a multifaceted view of their unstable crossroads
Recensión bibliográfica Del Llano Señarís JE, Campillo-Artero C, directores. Health technology assessment and health policy today: a multifaceted view of their unstable crossroads. En: Ortún V, director. Colección «Economía de la salud y gestión sanitaria». Madrid: Springer Healthcare Communications Ibérica; 2014. 156 p. ISBN: 978-84-940118-5-6
Receptor activator of nuclear factor kB ligand, osteoprotegerin, and risk of death following a breast cancer diagnosis: results from the EPIC cohort
Background Receptor activator of nuclear factor kappa-B (RANK)-signaling is involved in tumor growth and spread in experimental models. Binding of RANK ligand (RANKL) to RANK activates signaling, which is inhibited by osteoprotegerin (OPG). We have previously shown that circulating soluble RANKL (sRANKL) and OPG are associated with breast cancer risk. Here we extend these findings…
Reassessing the association between age at menarche and cardiovascular disease: observational and Mendelian randomization analyses
Aims Observational studies have shown a U-shaped association between age at menarche (AAM) and cardiovascular disease (CVD). We assessed non-linearity of the observational association and the potential causal relationship between AAM and CVD using data from the European Prospective Investigation into Cancer and Nutrition—Cardiovascular Disease (EPIC-CVD) study and the UK Biobank. Methods and results We…