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Vaccination strategies for patients under monoclonal antibody and other biological treatments: an updated comprehensive review based on EMA authorizations to January 2024

Artículos Científicos, Investigación

Introduction Monoclonal antibodies (mAbs) and other biological agents are being increasingly approved in the last years with very different indications. Their highly heterogeneous immunosuppressive effects, mechanisms of action and pharmacokinetics require comprehensive individualized vaccination schedules. Areas covered Vaccination for immunocompromised patients. Prevention and treatment with mAbs and other biological therapies. Expert opinion Current recommendations on…

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Uso de heurísticos y error diagnóstico en Atención Primaria: revisión panorámica

Artículos Científicos

Objetivo Evaluar la evidencia sobre el uso de heurísticos de representatividad, disponibilidad, anclaje y ajuste y exceso de confianza en la práctica clínica real, específicamente en el ámbito de la Atención Primaria. Diseño Revisión panorámica (scoping review). Fuentes de datos Bases de datos de OvidMedline, Scopus, PsycoINFO, Cochrane Library y PubMed. Con el fin de…

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Using longitudinal targeted maximum likelihood estimation in complex settings with dynamic interventions

Artículos Científicos

Longitudinal targeted maximum likelihood estimation (LTMLE) has very rarely been used to estimate dynamic treatment effects in the context of time‐dependent confounding affected by prior treatment when faced with long follow‐up times, multiple time‐varying confounders, and complex associational relationships simultaneously. Reasons for this include the potential computational burden, technical challenges, restricted modeling options for long…

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Use of the Therapy App Prescinde for Increasing Adherence to Smoking Cessation Treatment

Artículos Científicos

Tobacco use poses major health risks and is a major contributor to causes of death worldwide. Mobile phone-based cessation apps for this substance are gaining popularity, often used as a component of traditional interventions. This study aimed to analyze adherence to an intervention using a mobile phone application (App-therapy Prescinde (v1)) as a function of…

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Use of psychological interventions among healthcare workers over the 2-year period following the COVID-19 pandemic: A longitudinal study

Artículos Científicos, Investigación

Introduction Although healthcare workers (HCWs) have reported mental health problems since the beginning of the COVID-19 pandemic, they rarely use psychological support. Here, we described the use of psychological support among HCWs in Spain over the 2-year period following the initial pandemic outbreak and explore its association with workplace- and COVID-19-related factors measured at baseline,…

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Use of heuristics during the clinical decision process from family care physicians in real conditions

Artículos Científicos

Rationale aims and objectives The available evidence on the use of heuristics and their relationship with diagnostic error in primary care is very limited. The aim of the study is to identify the use of unknown thought and specifically the possible use of Representativeness, Availability and overconfidence heuristics in the clinical practice of primary care…

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Urinary levels of organophosphate pesticides and predictors of exposure in pre-school and school children living in agricultural and urban communities from south Spain

Artículos Científicos

Background. Despite the widespread use of organophosphate (OP) pesticides, information on predictors of children’s exposure to such pesticides is scarce. Objective. To assess exposure to OP pesticides in children 3-11 year-old living in agricultural communities and urban areas from Andalusia (Southern Spain), and to identify the main determinants of exposure. Methods. A longitudinal study was…

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Unprocessed red meat and processed meat consumption and risk of stroke in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC)

Artículos Científicos

Background/Objectives: High intakes of unprocessed red or processed meat may increase the risk of stroke. We aimed to examine the association between unprocessed red meat, processed meat and total red meat consumption and risk of total stroke and ischaemic stroke. Subjects/Methods: Cox proportional hazards regression analyses were conducted based on the data for 41 020 men…

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Uno detrás de otro: Factores que influyen en el abandono del ejercicio de la Medicina Familiar y Comunitaria en jóvenes médicos y médicas de familia. Un estudio cualitativo

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

FUNDAMENTOS // Una Atención Primaria fuerte tiene efectos beneficiosos para la salud. El atributo de la misma con mayores beneficios es la longitudinalidad, que requiere de estabilidad laboral para poder producirse. Además, la Atención Primaria se enfrenta a una crisis por el número de jubilaciones que espera. Conseguir la permanencia de los profesionales jóvenes en…