Background There is increasing evidence that diets characterized by food biodiversity could contribute to health outcomes. Greater dietary species diversity has been linked to reduced gastrointestinal cancer risk and all-cause mortality. However, mechanistic pathways supporting the association between food biodiversity and health are just beginning to be explored. Aim To characterize the metabolic profile associated…
Hepatocellular carcinoma (HCC) development entails changes in liver metabolism. Current knowledge on metabolic perturbations in HCC is derived mostly from case‐control designs, with sparse information from prospective cohorts. Our objective was to apply comprehensive metabolite profiling to detect metabolites whose serum concentrations are associated with HCC development, using biological samples from within the prospective European…
Background: Urothelial carcinoma (UC) is the predominant (95%) bladder cancer subtype in industrialised nations. Animal and epidemiological human studies suggest that hormonal factors may influence UC risk. Methods: We used an analytic cohort of 333 919 women from the European Prospective Investigation into Cancer and Nutrition Cohort (EPIC). Associations between hormonal factors and incident UC…
La línea de investigación ‘Estado de la Infancia y Adolescencia en Andalucía (EIA) del Observatorio de la Infancia en Andalucía aborda a través de una serie de indicadores básicos el análisis del estado actual y la evolución de los niveles de bienestar y calidad de vida de la infancia y adolescencia en nuestra Comunidad Autónoma.…
Background: The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: Over half…
En este libro de 1997 se hablaba de los trasplantes de órganos como una terapéutica bien consolidada de elección para pacientes con insuficiencia renal, cardíaca, hepática, pulmonar, etc. Los trasplantes tienen una característica singular: precisan del concurso indispensable de la población con sus donaciones de órganos. Los trasplantes plantean un triángulo cuidadano-donante, aparato sanitario, enfermo receptor. Además la comunicación…
Las crisis, las emergencias y las épocas de disturbios se han relacionado con un aumento de la violencia interpersonal, incluida la violencia hacia las mujeres. A raíz de la declaración de estado de alarma y confinamiento se han puesto en marcha nuevas medidas encaminadas a paliar el posible impacto de la violencia de género (Plan…
La pandemia por coronavirus está provocando una crisis de salud pública mundial sobre la que aún desconocemos gran parte de sus manifestaciones clínicas, comportamiento epidemiológico y abordaje terapéutico. También sus consecuencias de tipo social y económico son impredecibles a medio y largo plazo. España está siendo uno de los países más afectados, tanto en incidencia…
The predictive value of work ability for several health and occupational outcomes is well known. Maintaining the ability to work of all employees has become an important topic in research although some evidence suggests that some groups of workers need greater attention than others. Healthcare workers (x¯ = 54.46 ± 5.64 years) attending routine occupational…
Alcohol consumption is associated with higher risk of breast cancer (BC); however, the biological mechanisms underlying this association are not fully elucidated, particularly the extent to which this relationship is mediated by sex hormone levels. Circulating concentrations of estradiol, testosterone, their free fractions and sex‐hormone binding globulin (SHBG), were examined in 430 incident BC cases…
