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Association of Coffee Consumption and Prediagnostic Caffeine Metabolites With Incident Parkinson Disease in a Population-Based Cohort

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Abstract Background and Objectives Inverse associations between caffeine intake and Parkinson disease (PD) have been frequently implicated in human studies. However, no studies have quantified biomarkers of caffeine intake years before PD onset and investigated whether and which caffeine metabolites are related to PD. Methods Associations between self-reported total coffee consumption and future PD risk…

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Inflammation and Gut Barrier Function-Related Genes and Colorectal Cancer Risk in Western European Populations

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Gut barrier dysfunction and related inflammation are known to be associated with the development and progression of colorectal cancer (CRC). We investigated associations of 292 single-nucleotide polymorphisms (SNPs) from 27 genes related to endotoxins/lipopolysaccharide (LPS) sensing and tolerance, mucin synthesis, inflammation, and Crohn’s disease with colon and rectal cancer risks. Incident CRC cases (N=1,374; colon=871,…

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Association between pre-diagnostic circulating lipid metabolites and colorectal cancer risk: a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Altered lipid metabolism is a hallmark of cancer development. However, the role of specific lipid metabolites in colorectal cancer development is uncertain. Methods In a case–control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC), we examined associations between pre-diagnostic circulating concentrations of 97 lipid metabolites (acylcarnitines, glycerophospholipids and sphingolipids) and…

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Surgical Treatment in Post-Stroke Spastic Hands: A Systematic Review

Artículos Científicos

Background: For more than two decades, the surgical treatment of post-stroke spastic hands has been displaced by botulinum toxin therapy and is currently underutilized. Objectives: This article aimed to assess the potential of surgery for treating a post-stroke spastic upper extremity through a systematic review of the literature on surgical approaches that are adopted in…

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Dietary intake of dicarbonyl compounds and changes in body weight over time in a large cohort of European adults

Artículos Científicos, Cáncer, Igualdad, Investigación

Dicarbonyl compounds are highly reactive precursors of Advanced Glycation End-products (AGEs), produced endogenously, present in certain foods, and formed during food processing. AGEs contribute to development of adverse metabolic outcomes but health effects of dietary dicarbonyls are largely unexplored. We investigated associations between three dietary dicarbonyl compounds, methylglyoxal (MGO), glyoxal (GO), and 3-deoxyglucosone (3-DG), and…

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Circulating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women

Artículos Científicos, Cáncer, Investigación

Thyroid cancer (TC) is substantially more common in women than in men, pointing to a possible role of sex steroid hormones. We investigated the association between circulating sex steroid hormones, sex hormone binding globulin (SHBG) and the risk of differentiated TC in men and women within the European Prospective Investigation into Cancer and nutrition (EPIC)…

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Calibration and XGBoost reweighting to reduce coverage and non-response biases in overlapping panel surveys: application to the Healthcare and Social Survey

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background Surveys have been used worldwide to provide information on the COVID-19 pandemic impact so as to prepare and deliver an effective Public Health response. Overlapping panel surveys allow longitudinal estimates and more accurate cross-sectional estimates to be obtained thanks to the larger sample size. However, the problem of non-response is particularly aggravated in the…

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Respuesta a la crisis sanitaria de la COVID-19 desde la perspectiva de género: lecciones aprendidas

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objetivo Profundizar desde la perspectiva de género en las lecciones aprendidas durante la pandemia de COVID-19 para hacer frente a futuras crisis de salud. Método Estudio con informantes clave con experiencia en salud pública y género del Ministerio de Sanidad, Consejerías de las comunidades autónomas, Institut Català de la Salut, Hospital de La Princesa, Escuela Andaluza…

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Enfoque de derechos humanos en la respuesta a salud y migración en Chile: revisión documental

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objetivo. Analizar el reconocimiento de derechos a la salud de las personas migrantes en Chile en el marco normativo de salud. Material y métodos. Estudio de metodología mixta secuencial. La fase cualitativa incluyó un análisis documental de 37 instrumentos publicados hasta el año 2021 sobre acciones de salud dirigidas a población migrante. Mediante el análisis…

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Aborto en Melilla: barreras de océano y frontera

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objetivo Describir el recorrido que realizan las mujeres para abortar en Melilla, así como identificar y analizar las barreras para su acceso. Método Investigación cualitativa con un total de ocho entrevistas semiestructuradas realizadas durante 2022 a tres personas referentes en el tema del aborto de ámbito nacional y a cinco profesionales del Área de Salud…