Regional Versus Centralized Hta: Implications for the Assessment of Cancer Drugs

Different jurisdictions organize their health technology assessment (HTA) capacity in different ways. In theory, a centralized approach offers the potential to pool the scarce resources devoted to HTA and national recommendations can be issued to encourage a uniform development of services across the whole country. On the other hand, a regional approach could help in…

Pre-diagnostic polyphenol intake and breast cancer survival: the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

The aim was to investigate the association between pre-diagnostic intakes of polyphenol classes (flavonoids, lignans, phenolic acids, stilbenes, and other polyphenols) in relation to breast cancer survival (all-cause and breast cancer-specific mortality). We used data from the European Prospective Investigation into Cancer and Nutrition cohort. Pre-diagnostic usual diet was assessed using dietary questionnaires, and polyphenol…

Smoking and All-cause Mortality in Older Adults: Results From the CHANCES Consortium

ntroduction Smoking is known to be a major cause of death among middle-aged adults, but evidence on its impact and the benefits of smoking cessation among older adults has remained limited. Therefore, we aimed to estimate the influence of smoking and smoking cessation on all-cause mortality in people aged ≥60 years. Methods Relative mortality and…

Guía Práctica sobre Derechos Humanos en la Atención al Paciente. Capítulos Internacionales y Regionales actualizados

Este capítulo presenta las principales normas internacionales protectoras de los derechos humanos en la atención al paciente y examina como son interpretadas por los órganos supervisores de los tratados delas Naciones Unidas (ONU). El presente capítulo está dividido en tres apartados, el primero describe las fuentes internacionales clave bajo las que se rigen los derechos…