Technology-facilitated sexual violence against women and its health impact: a mixed-methods systematic review

Introduction Technology-facilitated sexual violence (TFSV) is a significant public health issue, profoundly impacting women’s health. This systematic review aimed to synthesize evidence on the association between TFSV and mental and physical health in women aged 16 years and older. Methodology Following PRISMA guidelines, a systematic search was conducted across seven databases (CINAHL, Embase, PubMed, PsycINFO,…

Frameworks encompassing intersectional perspective of artificial intelligence in healthcare. Scoping review

Objectives This study systematically evaluates how existing AI frameworks in healthcare address intersectional bias across the AI lifecycle and explores the mitigation strategies proposed. Study design Scoping review. Methods A scoping review was conducted per PRISMA-ScR guidelines, analyzing studies from 2014 to 2024. Searches included MEDLINE (Ovid), PubMed, EMBASE (Ovid), SCOPUS, ESCI, IEEE Xplore, and…

Optimising the European Code Against Cancer, 5th edition, to increase awareness of avoidable cancer risks in all socioeconomic groups

Although cancer is a leading cause of death in the European Union, around 40% of cases are preventable. The European Code Against Cancer (ECAC) was developed to inform citizens about key cancer-risk-reducing actions. This study aimed to identify effective ways to present the 5th edition of the code (ECAC5) to optimise awareness of cancer risks…

Transferable Exclusivity Extension Vouchers for Antimicrobials: Incentive Design, Implementation Challenges, and Policy Trade-Offs

Antimicrobial resistance (AMR) is one of the greatest threats to public health, and forecasts for 2050 are even worse. In response, the European Commission (EC) is proposing the Transferable Exclusivity Extension Voucher (TEEV), which aims to encourage the development of innovative antimicrobials. It consists of extending data exclusivity for a medicine selected by the beneficiary…

The 3V score and joint associations of low ultra-processed food, biodiverse and plant-based diets on colorectal cancer risk: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Background Diet may modify colorectal cancer risk. We investigated the associations of three dietary patterns, ultra-processed food (UPF) consumption, healthy plant-based food consumption, and food biodiversity, separately and combined into a “3V” score with risk of colorectal cancer. Methods This study used data from the prospective European Prospective Investigation into Cancer and Nutrition (EPIC) cohort,…

Cost-effectiveness of second- or third-line treatment with tisotumab vedotin for metastatic or recurrent cervical cancer

Objective To evaluate the cost-effectiveness of tisotumab vedotin (TV) versus single-agent chemotherapy in recurrent or metastatic cervical cancer (r/mCC) after failure of first-line treatment, from the perspective of the Spanish National Health System. Methods Cost-utility analysis was conducted using a partitioned survival model with three health states, over a 60-month time horizon. Efficacy data ‒overall…

Personalized prevention of neurodegenerative diseases: scoping review and evidence gap map

Neurodegenerative diseases represent a major public health challenge due to their high prevalence and poor prognosis. Identifying biomarkers to stratify individuals by their risk of developing these diseases may help to define new personalized prevention interventions. The objective of this study was to conduct a scoping review of biomarkers for primary and secondary personalized prevention…

The euthanasia law from the perspective of healthcare professionals in Spain

Background In 2021, Spain passed Organic Law 3/2021, which regulates euthanasia and represents an extension of rights to make decisions in the context of health care. According to the Law, the state must guarantee access to Medical Assistance in Dying (MAiD) through health services. Therefore, the involvement of health professionals is crucial. The aim of…

The relationship between psychological stress and cancer incidence: a systematic review and meta-analysis

This systematic review of prospective studies examined whether psychological stress—conceptualised as cumulative stressful life events or perceived stress—is associated with cancer incidence. It was pre-registered in PROSPERO (IDCRD42020175681) and conducted following PRISMA guidelines. Methodological quality was assessed using the NIH Tool for Observational Studies, and the certainty of evidence was assessed using the GRADE tool.…

Cost-Utility Analysis of Left Bundle Branch Area Versus Biventricular Pacing for Cardiac Resynchronization Therapy: A Multicenter, Prospective, Quasi-Experimental Study

Introduction Cardiac resynchronization therapy (CRT) is a well-established treatment for patients with heart failure (HF). Recently, left bundle branch area pacing (LBBAP) has emerged as a more physiological alternative to biventricular pacing (BVP) for CRT. This study aimed to evaluate the cost-utility of LBBAP CRT compared with BVP CRT. Methods A cost-utility, non-randomized, prospective, multicenter,…