Associations of residential and occupational history with the distribution of persistent pollutant mixtures in adipose tissue samples

This research aims to explore clusters of a mixture of 15 Persistent Toxic Substances (PTSs) in the adipose tissue of 227 individuals of an adult cohort from Granada Province (Southern Spain). Information about residence and occupation during participants lifetime was gathered by means of validated questionnaires. Clusters of pollutants in the study population were identified…

Kaposi sarcoma incidence, survival and trends: Data from the information network on rare cancers in Europe (RARECAREnet)

Background This study provides updated information on Kaposi sarcoma (KS) in Europe during 1995–2007 from the RARECARENet project. Methods Data comes from 59 population-based cancer registries in 22 countries. KS was defined as ICD-O-3 morphology code 9140 combined with any topography code. Crude and age-adjusted incidence rates and relative survival for years of diagnosis 2000–2007…

Risk Prediction for Renal Cell Carcinoma: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Prospective Cohort Study

Background: Early detection of renal cell carcinoma (RCC) has the potential to improve disease outcomes. No screening program for sporadic RCC is in place. Given relatively low incidence, screening would need to focus on people at high risk of clinically meaningful disease so as to limit overdiagnosis and screen-detected false positives. Methods: Among 192,172 participants…

PNS108 Proposal for a Core Evaluation Framework of Value Added Medicines

Objectives Through incremental innovation by repositioning, reformulating and combining of off-patent pharmaceuticals, value added medicines (VAMs) offer potential benefits at affordable R&D costs. Current evaluation frameworks are primarily designed for de novo pharmaceuticals, consequently the mismatch between evidence requirements by public decision-makers and the evidence generated by manufacturers prevents exploiting the full societal benefits of…

Atención sanitaria al malestar premenstrual. La perspectiva de las mujeres

Objetivo Existe una alta prevalencia de malestar premenstrual en las mujeres españolas que conlleva efectos negativos como el detrimento de su calidad de vida. Adoptando el enfoque biopsicosocial, este estudio pretende conocer las vivencias y las experiencias de las mujeres, indagar en sus creencias y actitudes sobre el síndrome premenstrual y la eliminación de la…

Interaction Between GAD65 Antibodies and Dietary Fish Intake or Plasma Phospholipid n-3 Polyunsaturated Fatty Acids on Incident Adult-Onset Diabetes: The EPIC-InterAct Study

OBJECTIVE Islet autoimmunity is associated with diabetes incidence. We investigated whether there was an interaction between dietary fish intake or plasma phospholipid n-3 polyunsaturated fatty acid (PUFA) concentration with the 65-kDa isoform of GAD (GAD65) antibody positivity on the risk of developing adult-onset diabetes. RESEARCH DESIGN AND METHODS We used prospective data on 11,247 incident…

Jornada sobre Psicología clínica en Atención Primaria en Andalucía

#PsicologíaClínicaAP Jornada sobre Psicología clínica en Atención Primaria en Andalucía Las cifras de incidencia de los trastornos mentales leves o moderados son muy elevadas, como también lo son las cifras de consumo de ansiolíticos o antidepresivos. El tratamiento con fármacos ha mostrado una nula o limitada efectividad en estos problemas frente a la mostrada por…