LupaDetalles

Combined Genome, Transcriptome and Metabolome Analysis in the Diagnosis of Childhood Cerebellar Ataxia

Artículos Científicos, Investigación, Mujeres EASP

Ataxia in children is a common clinical sign of numerous neurological disorders consisting of impaired coordination of voluntary muscle movement. Its most common form, cerebellar ataxia, describes a heterogeneous array of neurologic conditions with uncountable causes broadly divided as acquired or genetic. Numerous genetic disorders are associated with chronic progressive ataxia, which complicates clinical management,…

LupaDetalles

Cancer incidence estimation from mortality data: a validation study within a population-based cancer registry

Artículos Científicos, Investigación, Mujeres EASP

Background Population-based cancer registries are required to calculate cancer incidence in a geographical area, and several methods have been developed to obtain estimations of cancer incidence in areas not covered by a cancer registry. However, an extended analysis of those methods in order to confirm their validity is still needed. Methods We assessed the validity…

LupaDetalles

A Semiautomated Classification System for Producing Service Directories in Social and Health Care (DESDE-AND): Maturity Assessment Study

Artículos Científicos

Background: DESDE-LTC (Description and Evaluation of Services and DirectoriEs for Long-Term Care) is an international classification system that allows standardized coding and comparisons between different territories and care sectors, such as health and social care, in defined geographic areas. We adapted DESDE-LTC into a computer tool (DESDE-AND) for compiling a directory of care services in…

LupaDetalles

Transdisciplinariedad efectiva en el cuidado de la diabetes: Diagnóstico PRECEDE

Artículos Científicos

La diabetes mellitus (DM) es una enfermedad compleja y multifactorial que requiere un proceso integrado de actividades y diferentes niveles de medición de resultados1. El cuidado transdisciplinario (CTD) es la prestación conjunta que asocia diferentes entornos y disciplinas con interacciones continuas entre el sistema de salud y social en los que cada persona está inmersa…

LupaDetalles

Evaluation of conventional and non-conventional biomarkers of liver toxicity in greenhouse workers occupationally exposed to pesticides

Artículos Científicos

The liver plays a prominent role in maintenance of homeostasis and is the major organ for xenobiotic metabolism, including pesticides. Conventional liver function tests are widely used to assess hepatocellular and biliary system dysfunction by measuring serum levels of aminotransferases (ALT, AST) and cholestasis enzymes (alkaline phosphatase –ALP– and γ-glutamyl transferase –GGT–), respectively. Although these…