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Dietary Advanced Glycation End-Products and Colorectal Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study

Artículos Científicos

Dietary advanced glycation end-products (dAGEs) have been hypothesized to be associated with a higher risk of colorectal cancer (CRC) by promoting inflammation, metabolic dysfunction, and oxidative stress in the colonic epithelium. However, evidence from prospective cohort studies is scarce and inconclusive. We evaluated CRC risk associated with the intake of dAGEs in the European Prospective…

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COVID-19 en residencias de mayores: factores estructurales y experiencias que avalan un cambio de modelo en España

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

La pandemia de COVID-19 ha tenido efectos devastadores sobre las personas mayores que viven en residencias. En España, aproximadamente el 3% de los casos y el 40% de los fallecimientos han sido en este grupo de población, en el que además han aumentado los síndromes geriátricos y los problemas psicosociales, y se han vulnerado derechos…

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Changes in Caregiver Personal Support Networks: Gender Differences and Effects on Health (CUIDAR-SE Study)

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Technological changes have led to important advances in medical diagnoses and treatments that prolong the informal care process. Support from the personal network of informal caregivers is an undervalued resource and the changes that have occurred over time are unknown. The aim of this study was to analyze the changes in personal network support among…

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Evaluation of protein and amino acid intake estimates from the EPIC dietary questionnaires and 24-h dietary recalls using different food composition databases

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background and aims This study aimed to expand the European Prospective Investigation into Cancer and Nutrition (EPIC) nutrient database (ENDB) by adding amino acid (AA) values, using the U.S. nutrient database (USNDB). Additionally, we aimed to evaluate these new protein and AA intake estimates from the EPIC dietary questionnaires (DQ) and 24-h dietary recalls (24-HDR) using…

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Cost–Utility Analysis of a Medication Adherence Management Service Alongside a Cluster Randomized Control Trial in Community Pharmacy

Artículos Científicos

Background: It is necessary to determine the cost utility of adherence interventions in chronic diseases due to humanistic and economic burden of non-adherence. Purpose: To evaluate, alongside a cluster-randomized controlled trial, the cost-utility of a pharmacist-led medication adherence management service (MAMS) compared with usual care in community pharmacies. Materials and Methods: The trial was conducted…

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Introduction to computational causal inference using reproducible Stata, R, and Python code: A tutorial

Artículos Científicos

The main purpose of many medical studies is to estimate the effects of a treatment or exposure on an outcome. However, it is not always possible to randomize the study participants to a particular treatment, therefore observational study designs may be used. There are major challenges with observational studies; one of which is confounding. Controlling…

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Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background Unhealthy diets, the rise of non-communicable diseases, and the declining health of the planet are highly intertwined, where food production and consumption are major drivers of increases in greenhouse gas emissions, substantial land use, and adverse health such as cancer and mortality. To assess the potential co-benefits from shifting to more sustainable diets, we…

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Evidence Update on the Relationship between Diet and the Most Common Cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: A Systematic Review

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The European Prospective Investigation into Cancer and Nutrition (EPIC) is a multicentre prospective study conducted in 23 centres in 10 European countries. Here we review the findings from EPIC on the relationship between diet-related exposures and incidence or mortality from the four most frequent cancers in the European population: colorectal, breast, lung, and prostate cancer.…

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Salivary Melatonin Rhythm and Prostate Cancer: CAPLIFE Study

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Purpose: To analyze the association between salivary melatonin rhythm and prostate cancer (PCa). Materials and Methods: A total of 40 PCa cases and 41 controls from CAPLIFE study were analyzed to determine the salivary melatonin rhythm through 6 saliva samples. Amplitude (maximum melatonin peak) was categorized as low or high using the cut-off point median…