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Linking Nutri-Score dietary profiles to metabolic biomarkers in a cross-sectional study within the multinational EPIC cohort

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

The front-of-pack label Nutri-Score has been implemented in several European countries since 2017 to guide consumers towards foods of higher nutritional value. A few studies reported associations between Nutri-Score dietary profiles reflecting a lower nutritional quality, however not using the 2023-updated version of the algorithm, and profiles of biomarkers consistent with increased metabolic risk. Our…

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Mapping the landscape of managed entry agreements: a systematic review of global frameworks, system-level components, and implementation challenges

Artículos Científicos, Investigación

Background: Managed Entry Agreements (MEAs) are pivotal for enabling access to innovative pharmaceuticals while mitigating financial risk and addressing evidence uncertainty. Despite conceptual acceptance, the essential requirements for their design and implementation are poorly documented, posing a challenge for evolving health systems. This study aimed to systematically review and map global evidence published in the…

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Developing a framework to assess off-patent medicines policies in Latin America and the Caribbean

Background Countries in Latin America and the Caribbean (LAC) often lack a systematic approach to assessing the maturity and effectiveness of their policies for promoting off-patent (generic and biosimilar) medicines. Currently, no comprehensive, region-specific methodology exists that encompasses both generics and biosimilars. The objective of this paper is to develop a framework for assessing the…

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A data-driven framework for predicting PEG-defined MacroB12 in hypercobalaminemia

Cáncer, Investigación

MacroB12 interference presents a significant challenge in the diagnosis of Vitamin B12 status, potentially masking true deficiency. To establish robust predictors and quantify the utility of pre-polyethene glycol (PEG) B12 levels, we conducted a retrospective analysis of 875 individuals with hypercobalaminemia (>1000 pg/mL), using multiple imputation to handle missing data. Multivariable regression modelling revealed that PEG-defined…

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Assessing the role of ultra-processed foods in colorectal cancer incidence: insights from the EPIC cohort

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Studies have reported associations between ultra-processed food (UPF) consumption and colorectal cancer (CRC) incidence, yet the magnitude of these associations remains unclear. This study estimated the cohort-associated fraction (CAF), adapted from the population-attributable fraction metric, between UPF consumption and CRC incidence and explored the potential benefits of substituting UPFs with unprocessed or minimally processed…

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Premenopausal and postmenopausal obesity and endometrial cancer risk: circulating biomarkers of inflammation, insulin resistance, and sex hormones as mediators

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Obesity may increase endometrial cancer risk through pathways involving chronic inflammation, insulin resistance, and altered sex hormone levels. Methods Within the European Prospective Investigation into Cancer and Nutrition cohort, we investigated these mediating pathways using prediagnostic circulating biomarkers measured in 337 matched case-control pairs with postmenopausal measurements and 196 pairs with premenopausal measurements. We…

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IX Jornadas de Prevención de Riesgos Laborales

Jornadas, Jornadas y eventos

PROGRAMAINSCRIPCIÓNBASES COMUNICACIONESPrevención de Riesgos LaboralesIX Jornadas de Prevención de Riesgos Laborales del Servicio Andaluz de Salud Cuidar a quienes cuidan: innovación y prevención para una sanidad más segura Almería, 24 y 25 de septiembre de 2026 LUGAR DE CELEBRACIÓN: Auditorio del Hospital Universitario Torrecárdenas (Almería). DIRIGIDO A: Profesionales de las Unidades de Prevención y Directivos…