A multi-stakeholder multicriteria decision analysis for the reimbursement of orphan drugs (FinMHU-MCDA study)

Background Patient access to orphan medicinal products (OMPs) is limited and varies between countries, reimbursement decisions on OMPs are complex, and there is a need for more transparent processes to know which criteria should be considered to inform these decisions. This study aimed to determine the most relevant criteria for the reimbursement of OMPs in…

A prospective diet-wide association study for risk of colorectal cancer in EPIC

BACKGROUND & AIMS Evidence regarding the association of dietary exposures with colorectal cancer (CRC) risk is not consistent with a few exceptions. Therefore, we conducted a diet-wide association study (DWAS) in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the associations between several dietary exposures with CRC risk. METHODS The association of…

Cost-utility of talazoparib monotherapy treatment for locally advanced or metastatic breast cancer in Spain

Breast cancer is one of the most frequent malignancies. The aim of the article is to analyse the cost-utility ratio and budgetary impact of talazoparib treatment for patients with locally advanced or metastatic gBRCA + breast cancer from the perspective of the Spanish National Health System. Analyses were based on the EMBRACA clinical trial and the model was constructed…

A Mobile Phone-Based Intervention to Reduce Mental Health Problems in Healthcare Workers During the COVID-19 Pandemic (PsyCovidApp): Randomized Controlled Trial

Background: The global health emergency generated by the COVID-19 pandemic is posing an unprecedented challenge to healthcare workers (HCWs), who are facing heavy workloads under psychologically difficult situations. Objective: This trial aims to evaluate the effectiveness of a psychoeducational mobile Health (mHealth) intervention to reduce mental health problems in HCWs during the COVID-19 pandemic. Methods:…

Jornada IMID

Jornada Virtual: Actualización en Enfermedades Inmunomediadas (IMID)#EnfermedadesIMID Programa Inscripción JORNADA VIRTUAL Actualización en Enfermedades Inmunomediadas (IMID) #EnfermedadesIMID 20 y 25 de mayo de 2021   COORDINACIÓN CIENTÍFICA Dra. Maria José Sánchez Pérez. Profesora de la Escuela Andaluza de Salud Pública. Directora Científica de ibs.GRANADA. Granada Dr. Jose Javier Pérez Venegas. Coordinador del Plan Andaluz de…

Anticipated help-seeking for cancer symptoms before and after the coronavirus pandemic: results from the Onco-barometer population survey in Spain

Background The patient interval—the time patients wait before consulting their physician after noticing cancer symptoms—contributes to diagnostic delays. We compared anticipated help-seeking times for cancer symptoms and perceived barriers to help-seeking before and after the coronavirus pandemic. Methods Two waves (pre-Coronavirus: February 2020, N = 3269; and post-Coronavirus: August 2020, N = 1500) of the Spanish Onco-barometer population survey were compared.…

Soft drink and juice consumption and renal cell carcinoma incidence and mortality in the European Prospective Investigation into Cancer and Nutrition

Background: Renal cell carcinoma (RCC) accounts for more than 80% of kidney cancers in adults and obesity is a known risk factor. Regular consumption of sweetened beverages has been linked to obesity and several chronic diseases including some types of cancer. It is uncertain whether soft drink and juice consumption is associated with risk of…

Jornada virtual para la mejora de la atención y la accesibilidad a las personas con TEA

Programa JornadaTrabajo de CampoDocumentación de InterésVer Jornada Programa Formación de Formadores Jornada virtual para la mejora de la atención y la accesibilidad a las personas con Trastorno de Espectro del Autismo   Reconocimiento de Interés científico sanitario de la Secretaría General de Investigación, Desarrollo e Innovación en Salud de la Consejería de Salud y Familias…

Acción Comunitaria para ganar Salud

Guía Acción Comunitaria para ganar Salud…o cómo trabajar en común para mejorar las condiciones de vida Coordinación institucional: Ministerio de Sanidad. Dirección General de Salud Pública. Subdirección General de Promoción, Prevención y Calidad Coordinación técnica: Mariano Hernán García. Escuela Andaluza de Salud Pública Jara Cubillo Llanes. Ministerio de Sanidad ¿A quién se dirige esta guía?…

A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Background Vitamin B6 insufficiency has been linked to increased risk of cancer and other chronic diseases. The circulating concentration of pyridoxal 5′-phosphate (PLP) is a commonly used measure of vitamin B6 status. Ratios of substrates indicating PLP coenzymatic function and metabolism may be useful complementary measures to further explore the role of vitamin B6 in…