Omnivorous and plant-based dietary patterns: a comparative analysis using data-driven and index-based approaches

Background and objective Plant-based diet (PBD) followers are growing worldwide. The aim was to explore the dietary profile of PBDs, taking the omnivorous (OMN) diet as a reference. Methods A cross-sectional study was carried out. A total of 760 participants were included, of whom 161 self-identified as vegan, ovo-lacto-vegetarian, or pesco-vegetarian. Intakes of 175 foods,…

Circulating metabolites and fatty acids associated with ultra-processed food consumption: results from the EPIC study

Emerging evidence links consumption of ultra-processed foods (UPF) to higher risks of non-communicable diseases and mortality, but the underlying mechanisms remain unclear. This study aimed to identify molecular signatures of UPF intake in participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Foods were classified into four groups using the Nova system,…

Between Safeguard and Constraint: Navigating Patient Autonomy in Protective Laws for Medical Assistance in Dying

There has been an increase in the number of jurisdictions legalizing or decriminalizing Medical Assistance in Dying (MAiD). Legal frameworks worldwide strive to balance respect for autonomy with regulatory safeguards that both operationalize voluntary choice and prevent access to MAiD in cases of remediable despair or coerced decision-making. However, the implementation of such an equilibrium…

Immune Markers and Risk of Pancreatic Cancer in the European EPIC Cohort

The immune system is a major driver in pancreatic cancer development. Several prospective cohort studies have found associations for single immune system-derived proteins such as IL6 or CRP, but results are inconclusive, and Omics-based research is scarce. Hence, we aimed to investigate associations of a comprehensive protein panel with the risk of pancreatic cancer. Within…

Effectiveness of high-dose versus standard-dose influenza vaccines against severe respiratory and secondary cardiovascular outcomes in adults aged ≥80 years

Objectives Vaccination is a key measure to prevent severe influenza in adults aged ≥80 years, who experience the highest burden of respiratory and cardiovascular complications. Because immunosenescence reduces the effectiveness of standard-dose vaccines (SD-IIV), enhanced formulations such as high-dose vaccines (HD-IIV) are recommended in the elderly. Real-world data on their effectiveness in adults aged ≥80…

Mapeo de los activos para la salud y el bienestar del carnaval de Cádiz

El carnaval puede relacionarse con la promoción del bienestar, tanto desde las teorías participativas como las socioecológicas y las salutogénicas, centradas en factores que promueven la salud y potencian recursos positivos para afrontar la vida. Quienes participan activamente en el carnaval callejero de Cádiz pueden aportar una perspectiva de interés sobre la promoción de la…

Is cancer increasing in young adults in Spain? Incidence trends from the Spanish Network of Cancer Registries (REDECAN)

Introduction There is growing concern about rising cancer incidence among adults younger than 50 years. This collaborative study within the Spanish Network of Cancer Registries (REDECAN) aimed to examine cancer incidence trends in young adults in Spain. Material and methods This population-based observational study used data from 15 cancer registries. All newly diagnosed cancer cases…

Use of population-based cancer registry data to evaluate organized breast cancer screening programmes in Europe by mode of detection: a scoping review

Organized breast cancer screening programmes are a cornerstone of cancer control policy across Europe. Population-based cancer registries (PBCRs) play a central role in monitoring screening performance, outcomes, and programme quality. However, the extent and methodological approaches of registry-based evaluations across Europe have not been comprehensively synthesized. Following PRISMA-ScR guidelines, we conducted a scoping review of…