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Reproductive Factors, Sex Hormone Levels, and Differentiated Thyroid Cancer Risk: A Mendelian Randomization Study

Artículos Científicos, Investigación

Background: Differentiated thyroid carcinoma (DTC) is occurring three times more frequently in females than in males. However, the underlying biological mechanisms driving this discrepancy remain poorly understood. To investigate the causal role of sex hormones and reproductive factors in the risk of DTC, we implemented a two-sample Mendelian randomization (MR) analysis. Methods: We utilized genome-wide…

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Alcohol and smoking habits in association with hepatocellular carcinoma risk

We assessed hepatocellular carcinoma (HCC) risk associated with smoking and alcohol consumption and their interactions, using both questionnaire data and objective serum biomarkers. Information on smoking and alcohol consumption was collected at baseline from 450,112 participants of the EPIC cohort, among whom 255 developed HCC after a median follow-up of 14 years. In a nested case–control…

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Reassessing the association between age at menarche and cardiovascular disease: observational and Mendelian randomization analyses

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Aims Observational studies have shown a U-shaped association between age at menarche (AAM) and cardiovascular disease (CVD). We assessed non-linearity of the observational association and the potential causal relationship between AAM and CVD using data from the European Prospective Investigation into Cancer and Nutrition—Cardiovascular Disease (EPIC-CVD) study and the UK Biobank. Methods and results We…

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Sexual Dysfunction in Women With Eating Disorders: Systematic Review and Meta-Analysis

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Background Eating disorders (EDs) are common mental health conditions that impact people globally. Sexual health problems are also widely researched across various contexts. This paper explores the connection between these two areas by conducting a meta-analysis to assess sexual dysfunction (SD) in women with EDs compared to healthy individuals. Methods Multiple electronic databases were searched.…

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Gender Differences in Clinical Practice Regarding Coronary Heart Disease: A Systematic Review

Artículos Científicos, Investigación, Mujeres EASP

Background/Objectives: A systematic review was performed with the aim of analysing potential sex differences in the overall treatment of coronary heart disease (CHD). Methods: Studies published between January 2011 and November 2023 that conducted a sex-based analysis of the provision of any type of therapeutic measure to treat CHD were included. A search was performed…

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Inflammation and gut barrier function-related genes and colorectal cancer risk in western European populations

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Gut barrier dysfunction and related inflammation are known to be associated with the development and progression of colorectal cancer (CRC). We investigated associations of 292 single-nucleotide polymorphisms (SNPs) from 27 genes related to endotoxins/lipopolysaccharide (LPS) sensing and tolerance, mucin synthesis, inflammation, and Crohn’s disease with colon and rectal cancer risks. Incident CRC cases (N = 1374; colon = 871,…

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Conferencias Ciclo esalud

A la carta, Conferencias

El Director Gerente de la Escuela Andaluza de Salud Pública y la Dirección del XL Máster de Formación Permanente en Salud Pública y Gestión Sanitaria y XIX Máster Europeo en Excelencia en Salud Pública – Europubhealth+ tienen el honor de invitarte a asistir a la tercera sesión del CICLO DE CONFERENCIAS: DESAFÍOS EN GESTIÓN SANITARIA…

Guía rápida de vacunación en Andalucía 2025
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Guía rápida de vacunación en Andalucía 2025

MOOC, MOOC destacado

Guía rápida de vacunación en Andalucía 2025 Inscripción: ABIERTA Duración:  15 horas Plazas disponibles: sin límite Evaluación: Cuestionarios de autoevaluación Obtención de diplomaINSCRIBIRSE AL CURSOACCESO AL CURSOA quién va dirigido Esta actividad está dirigida a profesionales sanitarios (Enfermería, Medicina, Farmacia) del sistema sanitario de Andalucía implicados en la recomendación, administración y/o gestión de vacunas, especialmente…