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Uno detrás de otro: Factores que influyen en el abandono del ejercicio de la Medicina Familiar y Comunitaria en jóvenes médicos y médicas de familia. Un estudio cualitativo

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

FUNDAMENTOS // Una Atención Primaria fuerte tiene efectos beneficiosos para la salud. El atributo de la misma con mayores beneficios es la longitudinalidad, que requiere de estabilidad laboral para poder producirse. Además, la Atención Primaria se enfrenta a una crisis por el número de jubilaciones que espera. Conseguir la permanencia de los profesionales jóvenes en…

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Association of body shape phenotypes and body fat distribution indexes with inflammatory biomarkers in the European Prospective Investigation into Cancer and Nutrition (EPIC) and UK Biobank

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background The allometric body shape index (ABSI) and hip index (HI), as well as multi-trait body shape phenotypes, have not yet been compared in their associations with inflammatory markers. The aim of this study was to examine the relationship between novel and traditional anthropometric indexes with inflammation using data from the European Prospective Investigation into…

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An Umbrella Review of Cognitive Behavioural and Dialectical Behavioural Therapies to Treat Self-Harm and Suicidal Behaviour in Adolescents

Artículos Científicos

Background: The incidence of self-harm and suicidal behaviour in adolescents is increasing. Considering the great impact in this population, an actualization of the evidence of those psychological treatment’s excellence for suicidal behaviour. Thus, the aim of this paper is to compile the available evidence on the effectiveness of cognitive behavioural therapy and dialectical behavioural therapy…

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Molecular Mechanisms Linking Genes and Vitamins of the Complex B Related to One-Carbon Metabolism in Breast Cancer: An In Silico Functional Database Study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Carcinogenesis is closely related to the expression, maintenance, and stability of DNA. These processes are regulated by one-carbon metabolism (1CM), which involves several vitamins of the complex B (folate, B2, B6, and B12), whereas alcohol disrupts the cycle due to the inhibition of folate activity. The relationship between nutrients related to 1CM (all aforementioned vitamins…

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Association between exposure to organophosphate pesticides and cytokine levels in a population of flower workers in Mexico

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The ability of organophosphate pesticides to disturb immune function has been demonstrated by in vivo and in vitro studies, but evidence of such effects on humans remains scarce. To assess the association between organophosphate pesticides exposure and cytokine levels in Mexican flower workers, a cross-sectional study was carried out. A questionnaire was provided to 121…

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Pre-diagnostic plasma advanced glycation end-products and soluble receptor for advanced glycation end-products and mortality in colorectal cancer patients

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Advanced glycation end-products (AGEs), formed endogenously or obtained exogenously from diet, may contribute to chronic inflammation, intracellular signaling alterations, and pathogenesis of several chronic diseases including colorectal cancer (CRC). However, the role of AGEs in CRC survival is less known. The associations of pre-diagnostic circulating AGEs and their soluble receptor (sRAGE) with CRC-specific and overall…

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On the use of the healthy lifestyle index to investigate specific disease outcomes

Artículos Científicos, Investigación

The healthy lifestyle index (HLI), defined as the unweighted sum of individual lifestyle components, was used to investigate the combined role of lifestyle factors on health-related outcomes. We introduced weighted outcome-specific versions of the HLI, where individual lifestyle components were weighted according to their associations with disease outcomes. Within the European Prospective Investigation into Cancer…

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Economic Analysis of Cochlear Implants in Adults With Bilateral Severe-to-Profound Hearing Loss. A Systematic Review of the Literature

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

Objective To determine the cost-effectiveness or cost-utility of cochlear implants (CI) in adults with severe to profound bilateral hearing loss. Databases Reviewed PubMed (Medline), The Cochrane Library, Embase via Elsevier, EBSCOhost CINAHL, and Scopus. Methods The study included adult participants with severe to profound bilateral neurosensory hearing loss. The analysis encompassed quality of life improvements,…